Regenerative Medicine

Stem Cell Research & PRP Platelet Rich Plasma  treatment to rescue!

Dr. Dalal Akoury founder of AWAREmed Health and Wellness Center introduces Platelet Rich Plasma PRP in Myrtle Beach, South Carolina. Stem Cell Research helped us understand how PRP  Plasma Rich Platelet work. Dr. Dalal Akoury  discusses What is Platelet Rich Plasma and how Stem Cell Research helped the field of Regenerative Medicine? here in Myrtle Beach at AWAREmed Health and Wellness Resource Center

Stem Cell Research & PRP Platelet Rich Plasma treatment to rescue!

The Platelet Rich Plasma (PRP) consists of concentrated fibrin, stem cells, and platelets resulting in up to a five-fold increase in platelets and bioactive growth factors, that is what Stem Cell Research did to the field of Regenerative Medicine. Because it is so concentrated, PRP acts as a potent tissue growth stimulant, amplifying the natural process of tissue repair and healing. Studies show that PRP induces the production of new collagen, bone and cartilage cells at the site of the injection, rebuilding the joint cartilage and strengthening injured ligaments and tendons. This new collagen is naturally incorporated directly into your existing cartilage and ligaments, making them thicker and stronger.

Platelets are tiny blood cells that are critical to healing. They are the body’s primary source of bioactive tissue growth factors. The platelets contain thousands of growth factors which include:

  • CTGF (Connective Tissue Growth Factor)
  • PGDF (Platelet Derived Growth Factor)
  • TGF-β (Transforming Growth Factor-beta)
  • EGF (Epidermal Growth Factor)
  • GF (Insulin Growth Factor)
  • BFGF (Basic Fibroblast Growth Factor)
  • VEGF (Vascular Endothelial Growth Factor)

Together, these compounds control and regulate your natural healing process in response to injury and degenerative changes. By concentrating these growth factors and injecting them at the site of injury, a robust healing response is achieved, rejuvenating tissues damaged by injury, delaying and/or reversing degenerative changes, and osteoarthritis. Stem Cell Research & PRP Platelet Rich Plasma  treatment to rescue!

What is PRP Therapy and Stem Cell Research?

Platelet Rich Plasma (PRP)therapy is the name given to a treatment done to stimulate healing which involves injection of one’s own growth factors into injured areas. The treatment helps to regenerate damaged joints, tendons, ligaments, and bone with precisely directed injections. These injections are a part of a new field of Regenerative medicine and sometimes referred to as “Biosurgery”

Dr. Dalal Akoury  discusses discusses the benefits of PRP Used Primarily for Chronic Conditions here in Myrtle Beach at AWAREmed Health and Wellness Resource Center

PRP treatments have been used since 1980s to improve wound healing and bone grafting procedures by plastic and maxillofacial (mouth, jaw and neck) surgeons. Orthopaedic surgeons and sports medicine specialists have utilized this technology since 1990s. From Stem Cell Research & PRP Platelet Rich Plasma  treatment to rescue! many people have rejuvenated.

PRP use in sports medicine primarily has been for the treatment of chronic tendon conditions, but also for acute muscle injuries. According to a new study in the October issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), early outcomes of PRP appear promising. “Some believe that PRP may catalyze the body’s repair mechanisms at areas of injury, improve healing and shorten recovery time,” said study co-author Michael Hall, MD, a senior orthopaedic surgery resident at the NYU Hospital for Joint Diseases in New York. Recent study published in The American Journal of Sports Medicine 2010 concluded that “treatment of patients with chronic lateral epicondylitis (Tennis elbow) with PRP reduces pain and significantly increases function, exceeding the effect of corticosteroid injection.” Another study notes that “treatment with PRP injections is safe, and may be useful for the treatment of early degenerative pathology of the knee, aiming to reduce pain and improve knee function and quality of life”

The most common applications include:

  • tennis elbow (lateral epicondylitis);
  • Achilles tendonitis (inflammation and swelling of the Achilles tendon);
  • patellar tendonitis (inflammation of the patellar tendon, also called “Jumper’s Knee”);
  • rotator cuff tendonopathy.

Dr. Dalal Akoury  discusses Stem Cell Research and the safety of PRP Platelet Rich Plasma? here in Myrtle Beach at AWAREmed Health and Wellness Resource Center

Autologous (patient derived) PRP has been used for over 30 years as an aid in recovery following certain surgical, orthopaedic and dental procedures. There is thousands of research articles published on the safety of PRP. Research and clinical data show that PRP injections are extremely safe, with minimal risk for any adverse reaction or complication. Because PRP is produced from your own blood, there is no concern for rejection or disease transmission. There is a small risk of infection from any injection into the body, but this is rare. Some research suggests that PRP may have an anti-bacterial property which protects against possible infection.

Stem Cell Research & PRP Platelet Rich Plasma  treatment to rescue! help us understand PRP Process and Procedure

Stem Cell Research & PRP Platelet Rich Plasma treatment to rescue!

During in-office PRP procedure, patient’s own blood is drawn, spun and enriched to isolate platelets and stem cells. These spun platelets are up to five fold more concentrated than in normal blood. Physician then identifies the proper location for regenerative injection, the exact structure and/or component of the injured area or an arthritic joint. When PRP is injected it stimulates the tendon or ligament causing mild inflammation that triggers the healing cascade in musculoskeletal injuries and arthritis, and allows even a severely damaged tissue to heal.

Most patients don’t require anything more than cold pack for pain from the procedure. Often, following a PRP injection, an “achy” soreness is felt. This “soreness” is a positive sign that healing has been set in motion. The soreness can last for several days but gradually decreases as healing and tissue repair occurs.
It is important that anti-inflammatory medications such as Ibuprofen, Aleve, Advil, and Aspirin be avoided following PRP treatments. These medicines may block the effects of the PRP injection. While many patients find it best to rest the area for several days after PRP, as long as you are responsible you can resume normal activities following I treatment. You should avoid anything other than light activity however for at least several days after injection.

Following the initial treatment a follow up visit will usually be scheduled within 2-3 weeks. At that time a decision may be made regarding the need for additional treatment. In general, chronic or severe injuries require more treatment then mild injuries. Restorative therapy including exercise or physical therapy may be prescribed as well.

Stem Cell Research & PRP Platelet Rich Plasma  treatment to rescue! helped Tendon Injuries

PRP is increasingly used in treatment of chronic non-healing tendon injuries including the elbow, patella, and the achilles among others. As a result of mechanical factors, tendons are vulnerable to injury and stubborn to heal. Tendons also bear the responsibility of transferring a great deal of force, and as a result are susceptible to injury when they are overwhelmed. With repetitive overuse, collagen fibers in the tendon may form micro tears, leading to what is called tendonitis. The injured tendons heal by scarring which adversely affects function and increases risk of re-injury. Furthermore, tendons heal at a slow rate compared with other connective tissues, secondary to poor vascularization (blood supply).

Traditional therapies to treat these conditions do not alter the tendon’s inherent poor healing properties and involve long-term palliative care. Corticosteroids are commonly injected, however studies suggest adverse side effects including atrophy and permanent adverse structural changes in the tendon. Medications including NSAIDs, while commonly used for tendinopathies, carry significant long-term risks including bleeding ulcers and kidney damage. Thus, clinical use of PRP treatments is growing.

Stem Cell Research & PRP Platelet Rich Plasma  treatment to rescue! PRP improves Elbow Injuries

A 2006 study in the American Journal of Sports Medicine, evaluated 140 patients with chronic epicondylar elbow pain. Of those patients, 20 were surgical candidates who had failed conservative treatments. The PRP treatment group noted 60% improvement at 8 weeks, 81% at 6 months, and 93% at final follow-up at 12–38 months. Of note, there were no adverse effects or complications. Additionally, there was a 94% return to sporting activities and a 99% return to daily activities.

Stem Cell Research & PRP Platelet Rich Plasma  treatment to rescue! PRP is proven to speed up  Wound healing

Non-healing wounds represent a challenging problem and are commonly related to peripheral vascular disease, infection, trauma, neurologic and immunologic conditions, as well as metabolic disorders.

Stem Cell Research & PRP Platelet Rich Plasma treatment to rescue!

Stem Cell Research & PRP Platelet Rich Plasma treatment to rescue!

A wound study published in the Journal of American Podiatry Medical Association 2006, involved 24 patients with 33 chronic non-healing lower extremity wounds. Patients failed conservative treatment for 6 months with a lack of reduction of surface area. The wounds were injected with PRP every 2 weeks. Successful wound closure was obtained in 20 wounds. Five wounds displayed no improvement. These findings were particularly significant because all patients had failed previously available treatment methods.

 

Stem Cell Research & PRP Platelet Rich Plasma  treatment to rescue!

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