What is a mitochondrion?
They are also sometimes referred to as the powerhouses. It is a membrane bound organelle which is found in most of the cells (eukaryotic cells) that make up living things.
As we mentioned earlier, mitochondria are also referred to as powerhouse due to the functions that they do in our bodies. Their main work is to generate the energy that our body cells require in order to execute their jobs. One of such cells which need a lot of energy is the brain cells. The brain cells are responsible for the communication to all the other parts of the body and thus these mitochondria must be transported along the cells.
Mitochondria generate chemical energy similarly to the one we normally get from batteries. This energy which is generated by the mitochondria in the form of chemical is referred to as Adenosine Triphosphate or simply ATP. This is an energy currency that every ling thing cell can use and this is what makes it possible for us to be kept alive.
Most of the addictive drugs cause damage in the body organs. For instance, alcohol may cause damage to the liver, muscle weakness as well as brain damage in severe cases. Any attempt to help the patent recover from the addiction must therefore apart from treating the addiction itself focus on the damage that has been caused by the addictive drug on the various body organs.
Any cure for addiction that doesn’t address the damage caused by the drug is considered incomplete since even after the patient recovers from the addiction, he/she will suffer from other illnesses which may come as a result of the damage caused by the drug. On top of this, some of the prescription addiction recovery drugs have been found to have residual effects on the body of the addict even after recovering from the addiction.
Mitochondrial restoration is a natural process that seeks to restore the various body organs which have been previously cellular affected to their normal working state. The mitochondrial restoration targets the organs that have been affected by the addictive drug and hence whose functional capacity has been also been affected but the drug and then restores its functional state.
Addiction is known to first affect the human brain before the drug even has any effect to the other related organs. In this case therefore, the treatment of addiction must address the damage that has been caused to the brain by the drug. Mitochondrial restoration is an appropriate natural way of treating addiction, since it helps in the restoration of the various body organs to their normal working states.
As earlier mentioned, the core mandate of mitochondria in the body is to produce the energy required by the cells in the body. The mitochondrial energy production is usually accompanied by two very closely linked metabolic processes. These processes are; a) the citric acid cycle also known as the Krebs/ biological fuel and b) an oxidative phosphorylation (OXPHOS).
- The citric acid cycle
This is usually a series of chemical reactions which are used by all aerobic organisms to generate energy via the process of oxidation of acetate which is derived from the food. The acetate is converted into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). This cycle also provides some precursors of certain amino acids as well as the reduction of the NADH that is used in a number of other biochemical reactions in the body.
- Oxidative phosphorylation
This is the pathway through which the mitochondrion which is released by the oxidation of nutrients is transported to the cells. They use its structure, enzymes and energy released by the oxidation processes to reform ATP. ATP is an important molecule in the body, as it works to supply energy to all the metabolic processes.
OXPHOS operates through a network of electrons, five protein complexes which are attached in the inner membrane of the mitochondria. The five protein complexes are: –
- Complex I also called NADH dehydrogenase
- Complex II known also as succinate dehydrogenase
- Complex III (the cytochrome-c reductase)
- Complex IV referred to as cytochrome-c oxidase
- Complex V (this is the ATP synthase)
The oxidative phosphorylation converts adenosine di-phosphate (ADP) to adenosine triphosphate (ATP). This is the chemical currency of cells and can then be transported to the cells where work needs to be done.
The aim of mitochondrial restoration is to ensure that the cells in the body are provided with the energy that they need to function. By ensuring that the cells are working correctly, makes it possible for the addict’s body organs to heal from the damage caused by the drugs. This ensures that the addict is healed inside out from the addiction and its damages it had caused to the addict’s body. This also helps to ensure that the recovery process doesn’t experience withdrawal symptoms and craving. This process though may take some time to complete; it provides a permanent solution to the addict as well as improving the overall well-being.