Amyotrophic Lateral Sclerosis often abbreviated as ALS is among the most dangerous degenerative disorders. Resulting from a progressive degeneration of the neurons, ALS is one of the brain illnesses characterized by continuous death of brain cells affecting the neurons that are located in the spinal cord area as well as the brain.
Some studies have shown that two out of a million suffer ALS each year. The number has continuously grown and forced medical experts as well as scientists to look for an effective treatment approach based regeneration of neurons’ cells so as to restore the functioning of the brain.
As we all know, the brain is one thing that a body can’t survive without. Its purpose is to control and coordinate every part of the body. One of the reasons, it is considered the best in handling whole body functions is the fact that it can effectively network each and every information sent to the brain via particular stimuli and conveyed via neurons in a useful manner.
The cells (motor neurons) affected by ALS functions best to pass down every information that comes from the brain to several muscle parts in the body through a spinal cord.
The neural damage might result depending on factors that involve several risks including generation of protein flakes, alteration of the genes and more. When any of these happens, chances that the passage of information will be compromised are high increasing the likelihood of the neurons to be damaged.
If the required information can’t be sent, the muscle of which the message was intended and that controls voluntary movements will weaken. And that is the reason most ALS victims end up being paralyzed or in some cases dead due to their dysfunctional respiratory system. One unfortunate fact is that no effective ALS treatment has been found yet.
What causes ALS?
As mentioned earlier, ALS might be encouraged by some factors that include manipulation of the genes with other environmental factors. Almost 10% of ALS cases are claimed to result from inheritance of potent genes. This is evident because only a few cases have been solved by technologies such a stem cell therapy.
Stem cell as a cure for ALS
Stem cell technology involves the production of cells intended for a particular tissue. Their primary purpose is to restore the functionality of the damaged organs. Due to this, stem cell therapy is considered as one of the best remedies for ALS simply because it can be used to regenerate new neuronal cells. It can also be used to prevent the damage of the tissues from further progressing.
How Stem Cells Work
Stem cells are always obtained from the body of a patient. Autologous sources include adipose tissue and bone marrow known to be among the best options for mesenchymal and hematopoietic stem cells. These two works best together. For example, hematopoietic stem cells are used for different purposes that include enhancing the immune system, stopping the damage from progressing, and more while mesenchymal stem cells differentiate into several nerve cells and supports the cells to improve on the results.
Available data has proven that stem cells are capable of treating ALS.