Category Archives: aLCOHOL DEHYDROGENASE

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Severe alcohol risks

Severe alcohol risks: The strong killer drink

Severe alcohol risks

Severe alcohol risks are evident in most societies seeing how people are wasting away

Alcohol is not only the number one addictive substance but also the leading killer drink. Doctor Dalal Akoury MD, President and founder of AWAREmed Health and Wellness Resource Center states the severe alcohol risks categorically because it is not a joke as people take it. In its way, alcohol death trap doesn’t spear anybody. Both users and innocent non users fall victims. Because of the magnitude of alcohol effects, it may not be easy to list holistically all the consequences of alcohol drinking. However, we can highlight a few like, heart attack, diabetes, heart failure and stroke or lung disease. Users of alcohol particularly addicts, are subjecting their life to several risks including:

  • Regular alcohol users have a higher rate of death from injury, accidents or violence triggered by alcohol consumption.
  • Alcohol overdose may lead to death particularly with young people in adolescence stage. As they make efforts in discovering themselves, they often want to impress their peers by demonstrating their ability to drink alcohol. The feelings of belonging motivates them into taking alcohol in total disregard of its effects. This can lead to alcohol overdose which does not only occur from any one heavy drinking incident, but may also occur from a constant infusion of alcohol in the bloodstream.
  • Severe withdrawal and delirium tremens which occurs in about 5% of alcoholics. It includes progressively severe withdrawal symptoms and altered mental states and in some cases, it can be fatal.
  • Frequent, heavy alcohol use directly harms many areas in the body and produce dangerous health conditions like liver damage, pancreatitis, anemia, upper gastrointestinal bleeding, nerve damage, and erectile dysfunction.
  • Alcohol abusers who need surgery have an increased risk of postoperative complications, including infections, bleeding, insufficient heart and lung functions, and problems with wound healing.

Severe alcohol risks: Hangover

Though hangover may not have direct medical problem, it definitely have significant consequences. Like for instance, changes in liver function, hormonal balance, and mental functioning and an increased risk for depression and cardiac events.

It can impair job performance, increasing the risk for mistakes and accidents and are generally common in light-to-moderate drinkers than heavy and chronic drinkers, suggesting that binge drinking can be as threatening as chronic drinking.

Severe alcohol risks: Accidents, Suicide, and Murder

Finally, majority of deaths on our roads are facilitated by drink driving giving alcohol lead role in accidents, suicide, and crime because:

  • Alcohol plays a major role in more than half of all automobile fatalities across the globe.
  • Alcohol-related automobile accidents are the leading causes of death in young people.
  • When it comes to alcohol we do not have favorable limits for safe drinking because two drinks can impair the ability to drive and even one drink may double the risk of injury, and more than four drinks increase the risk by 11 times therefore the only safe way is not drinking at all.
  • Alcoholism is the primary diagnosis in a quarter of all people who commit suicide.
  • Alcohol is implicated in over half of all murder cases, with this ratio of one to one you can only desire to stop drinking.

We can pool together in defeating this scourge by scheduling an appointment with doctor Akoury for the commencement of your recovery process.

Severe alcohol risks: The strong killer drink

 

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Alcoholism

Acetaldehyde roles and Alcoholism

Acetaldehyde roles

Acetaldehyde roles and Alcoholism works by categorizing alcoholism treatment solutions primarily to defeat addiction

Acetaldehyde roles and Alcoholism: Hydrogen atoms

Did you know that for every alcoholic beverage you take about 2 to 8 percent is lost through urine, sweat, or the breath? This means that the other 92 to 98 percent is metabolized by your body. All ethyl alcohol which is broken down in the human body is first converted to acetaldehyde, and then this acetaldehyde is converted into acetic acid radicals known as acetyl radicals. Acetaldehyde is a poison which is closely related to formaldehyde. Acetic acid is the essential component of vinegar. The acetic acid radical is the combining form of acetic acid. This acetic acid radical combines with Coenzyme A to form acetyl-CoA. The acetyl-CoA rhen enters the Krebs cycle, which is the basic powerhouse of the human body. Inside the Krebs cycle this acetyl radical is eventually broken down into carbon dioxide and water.

According to the experts at AWAREmed Health and Wellness Resource Center under the leadership of doctor Dalal Akoury MD, there are three different enzymes which the body uses to convert alcohol to acetaldehyde. All these enzymes work by stripping two hydrogen atoms off from the alcohol molecule which then converts the alcohol molecule into a molecule of acetaldehyde. We are going to be discussing the first one as indicated below and progressively conclude with the remaining two in our next article. And even as we do that, we appreciate that this article may be technical for many people and that is why if you have any concern about alcohol consumption, you can always schedule an appointment with doctor Akoury for a more professional breakdown of facts. The three enzymes which can convert alcohol to acetaldehyde are:

  • Alcohol dehydrogenase (ADH)
  • Cytochrome P450 (CYP2E1)
  • Catalase

Each of these enzymes is found in different parts of the body and each of them handles the hydrogen atoms which are stripped off from the alcohol molecule in a different way.

Acetaldehyde roles and Alcoholism: Alcohol dehydrogenase

The name “alcohol dehydrogenase” sounds like quite a mouthful, but it is quite self-explanatory if we break it down into its component parts. “de-” is a prefix which means “to remove”. We find it in such words as “dethrone” which means “to remove from the throne”. “-ase” is a suffix which means “enzyme”. Any time you see a chemical term which ends in the suffix “-ase” you know that you are dealing with an enzyme. “hydrogen” means “hydrogen” of course. So “de-hydrogen-ase” means “an enzyme which removes hydrogen atoms”, and “alcohol dehydrogenase” means “an enzyme which removes hydrogen atoms from the alcohol molecule”. The name alcohol dehydrogenase is sometimes abbreviated to ADH.

Alcohol dehydrogenase is the workhorse of the alcohol enzymes it breaks down the majority of the alcohol that enters the human body. Alcohol dehydrogenase is actually the name for a family of enzymes which break down alcohol–each of which has a slightly different molecular structure. Researchers have identified as many as 10 varieties of the alcohol dehydrogenase molecule. All of them bring about the same chemical reaction–the difference is that some varieties of alcohol dehydrogenase work more efficiently than others.

The alcohol dehydrogenase molecules do their work primarily in the stomach and the liver, although traces of them are found in other tissues as well. The hydrogen which is released when alcohol dehydrogenase turns alcohol into acetaldehyde is bound to a compound called NAD+ (Nicotinamide Adenine Dinucleotide) to form NADH (this is short for Nicotinamide Adenine Dinucleotide plus Hydrogen). Alcohol dehydrogenase does its work in the cellular fluid (cytosol) of the cell. If you dint know, now you know and for more clarification, call doctor Akoury now.

Acetaldehyde roles and Alcoholism: Hydrogen atoms

http://www.awaremednetwork.com/

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