Cancer – related thrombosis has been one of the leading causes of morbidity and mortality in patients. Its significance has been underscored by the fact that the condition can actually affect patients regardless of the stage at which the disease is. In this essay, we shall discuss an integrative approach that can be used to inhibit this condition in cancer patients. Basically, the approach that is used seeks to do two important things: make the tumor host terrain conducive to optimal health while being non – conducive to the growth and development of cancer cells through metastasis. Our focus shall be on different ways by which this objective can be achieved.
How cancer cells use angiogenesis to grow
The growth and development of cancer takes place through a series of complex and interrelated steps. An important thing to understand, though, is that for cancer cells to successfully grow, they have to be provided by a regular supply of oxygenated blood. This calls for a rich supply of blood vessels in the body of the patient. In general, a normal human body has an inbuilt mechanism by which new blood vessels are generated and develop for specific functions. This process, called angiogenesis, is vital for different purposes such as general healing of a wound and even during the process of embryo formation. Unfortunately, it is this processes that cancer cells make use of to achieve what they need most: blood supply. The cells literally hijack the process of angiogenesis and use it as a basis to support their growth and possible metastasis in the future.
The process of metastasis
It is important to note that metastasis of cancer cells occurs in several interconnected steps. First, after apparently normal cells of the body have been changed into completely tumor cells, a heavy network of capillaries is built around the cells. This process, angiogenesis, is necessary for the cells to develop and grow further. Research has indicated that cancerous cells are able to hasten the process by producing factors that promote angiogenesis. This build up in supply is necessary for the cells to get to the next stage which is invading the body cells of the host. After invading local body cells the newly develop cancer cells then undergo a process of breaking free from the original mass and spreading to other parts of the body. Cancer cells, in singular or groups, break away from the original mass and get spread through the supply system of the body. Although some are destroyed, there is always a good amount of cells which survive. It is the surviving cells that move across the body, find a new organ or tissue upon which to base their growth and begin the process of getting a new supply of blood afresh. This sets a new foundation for the process to repeat itself.
The role of Angiogenesis
It is the role that angiogenesis plays in this process that has stimulated a lot of research in use of therapies that inhibit it. The thinking behind this approach is that once the process has been inhibited, cancer cells will be deprived of their most vital resource: blood supply thus being condemned to an early death. The crux of the matter, however, is that with the use of anti – angiogenesis drugs comes the risk of cancer – related thrombosis. The problem is complicated further when one considers that different types of conventional cancer therapies have also been known to increase the possibility of the occurrence of cancer – related thrombosis in cancer patients.
Integrative approach to treat cancer – related thrombosis
This, therefore, calls for an integrative approach to treatment that arrests the process of metastasis while at the same time promoting optimal growth and reducing the possibility of cancer – related thrombosis. There are several things that such an approach is made up of which include the use of botanicals, botanical compounds, enzymes, nutritionals, diet and life-style changes.
- Lifestyle changes
It is important for cancer patients to carefully observe their lifestyles. Leading a healthy and active lifestyle plays a key role in reducing the possibility of one developing any of the different forms of cancer – related thrombosis. Furthermore, by using a diet that contains foods rich in different minerals such as vitamin E, omega – 3 fatty acids and polyphenol, it has been established that one would be reducing the possibility of such an occurrence.
- Use of botanicals
There are several different botanicals that have been used to reduce angiogenesis and, by extension, occurrence of cancer – related thrombosis in patients. For instance, some herbs used in Traditional Chinese Medicine have been found to exhibit these properties. Also, green tea, which contains a relatively high proportion of polyphenols, can be a useful product. However, the bulk of research on this score has been on botanicals such as Chinese wormwood Curcumin. The research has been focused on how particular agents found in these plants can be used effectively to counter the effects of particular cancer therapies in promoting the process of angiogenesis upon which metastasis and cancer – related thrombosis are based.
For years, our focus here at AWAREmed, has been to use the best available practices to ensure that our patients are free from the possibility of cancer – related thrombosis. To achieve this, we use a sound approach that is completely personalized to the needs of our clients, thus guaranteeing them the best services in integrative approach to cancer treatment.