Tag Archives: Adenosine triphosphate

Stem Cell Treatment for Autism Spectrum Disorders

Stem Cell Treatment for Autism Spectrum Disorders

The medicinal properties of the stem cells have seen it being used for treatment of myriad ailments or as therapy for many diseases that are not even treatable. for the cases of these diseases that are not treatable the stem cell therapy helps to alleviate on the dangerous symptoms of the diseases and offer comfort as well as lengthen the lives of those who are victims of these diseases. needless the stem cell therapy has become a crucial component of regenerative medicine with many researchers still working around the subject to find out how its applicability can be useful in treating lifestyle diseases that have become a problem to this generation and many generations to come. The stem cell therapy has been proposed as an effective therapy in cases of autism. Autism spectrum disorders are complex neurodevelopmental disorders. This term refers to a heterogeneous group of varied conditions characterized by dysfunctions in social interactions, skills, and communication, restricted interests, and repetitive stereotypic verbal and non-verbal behaviors, influencing the ability to relate to others. Cognitive, emotional and neurobehavioral abnormalities characterize the core symptoms. The prevalence of these disorders has dramatically increased in the last years, with present rates of 1 in every 88 children aged 8 years in the United States, according to Centers for Disease Control.

Autism Spectrum Disorders

Autism Spectrum Disorders are presumed to be a lifelong disability with multiple impacts on child and adult health. Without a doubt, adult autistic individuals show limited independence because of their learning disability. Adult patients of autism spectrum disorders experience problems in communication. They are not able to read and write well. They’ve got poor comprehension of whatever they read. Apart from impaired communication, they also exhibit stereotyped behaviors and restricted interests. The children affected require special and intensive parental, school, and social support without which coping with the condition may become a nightmare. Autism Spectrum Disorders results in a substantial impact not only on the person’s quality of life but also that of their family. Autism Spectrum Disorders patients are not very easy to take care of, apart from their impaired social behavior, the cost of caring for them is so high. It is estimated that the cost of caring for a single person suffering from Autism Spectrum Disorders for a life time is $3.2 million, therefore this disease by all means is a global problem that should be prioritized and fought from all fronts.

Though the most salient symptoms of these diseases is seen in the cognitive, emotional and neurobehavioral abnormalities, Autism Spectrum Disorders are also characterized by a broad range of biochemical, toxicological and immune involvement, including oxidative stress, endoplasmic reticulum stress, decreased methylation capacity, limited production of glutathione, mitochondrial dysfunction, intestinal dysbiosis, increased toxic metal burden, and immune dysregulations including autoimmunity. Due to these complex problems there has never been any effective medication for autism spectrum disorders that has shown dependable level of efficacy. Today there are only few medications that are licensed by FDA for treating autism related disorders. Needless to emphasize these medications that are available in pharmacies such as anti-psychotics have failed to address the core symptoms of autism spectrum disorders. These medications are quite palliative and have potential adverse effects on the user. For this reason there are other alternative treatments of Autism Spectrum Disorders that have since surfaced. these may include; behavioral, nutritional, and biomedical approaches therefore this creates a vacuum that can be filled with effective therapies like the stem cell therapy but still there is need for more research that a better treatments for this disorder can be found. Despite medical technology advancements it is good to be blunt, Autism spectrum disorders are still untreatable pathologies. Mesenchymal stem cells possess the immunological properties which make them promising candidates as a novel therapeutic option but there is no single therapy that has been found that can treat autism spectrum disorders.

This is how stem cell therapy works for autism

Autism Spectrum DisordersAs mentioned earlier Stem cells are precursors of all cells and are capable of forming cells of other types hematopoietic, nervous and cardiovascular system, endocrine organs, bone, cartilage and muscle tissue. It is with this ability of stem cells to shift shape that it can be harnessed to help treat autism. Early animal studies have shown that stem cells isolated from umbilical cord blood can stimulate cells in the spinal cord to regrow their myelin layers, and in doing so help restore connections with surrounding cells. Autism is thought to result from impaired connectivity in the brain. Because of this, it is practical to apply this therapy on patients with autism spectrum disorders besides Mesenchymal stem cells can regulate the immune system. the mesenchymal stem cells can also help to reverse inflammatory conditions and perhaps this is why very many institutions in the US and across the globe have been doing trials on ability of the stem cells to treat even Cohn’s disease which is a condition resembling the gut inflammation in autistic children. Autism is a serious disease that should be prioritized by the public health stakeholders plus you also need information on how to leave with this disease, Visit us at AWAREmed Health and Wellness Resource Centre at Myrtle Beach, South Carolina. Dr. Dalal Akoury (MD) an expert in integrative and regenerative medicine will be able to help.

Stem Cell Treatment for Autism Spectrum Disorders

 

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Chronic Fatigue and NAD Treatment

Chronic Fatigue and NAD Treatment

Chronic fatigue is very common among modern population. Studies have shown that over 9 million Americans today suffer from chronic fatigue. It affects people differently in that some may have a mild form of chronic fatigue while in others it may be severe. The severe form of chronic fatigue leads to a condition called chronic fatigue syndrome.

So what is chronic fatigue syndrome?

It is a debilitating disorder that affects a number of organs and is characterized by intense fatigue. This kind of fatigue worsens with mental or physical activity and does not go away easily even with bed rest. The symptoms of chronic fatigue include general body weakness, impaired memory, muscle pains, depression, anxiety and insomnia. Because chronic fatigue affects more than one body system, it ends up affecting the quality of your life.

People who suffer from chronic fatigue syndrome end up spending most of their time in bed due to the pains that accompany the condition. The condition is not easily diagnosed and some patient who exhibit similar symptoms end up being diagnosed with other conditions. Fibromyalgia (FMG) is one condition that tends to be every similar with chronic fatigues syndrome.

Fibromyalgia is characterized by symptoms such as prolonged muscle pains and tenderness. Fatigue, sleep disorders and impaired memory are also conditions that accompany FMG. The two conditions are however treated along the same line. The only difference is that in case of FMG, muscle pains prevail over other symptoms.

Chronic Fatigue

Causes of Chronic Fatigue

The official cause of the condition is still unknown. However, several studies point to certain factors that may indeed cause the symptoms associated with chronic fatigue syndrome.

Hormonal Imbalances: most patients with chronic fatigue syndrome in one way or another suffer from hypothyroidism and adrenal fatigue. The thyroid and adrenal hormone are responsible metabolism regulation. In this case, low levels of these hormones in the body cause energy levels to decline thus causing fatigue.

Toxics: compounds such as pesticides, herbicides contain toxics that poison the mitochondria and thereby affecting the production of energy that leads to symptoms of fatigue.

Mitochondrial dysfunction: the mitochondria are very vital in the body for the production of energy. When the mitochondria are not functioning as they should, energy production for the cells is affected. The body thereby ends up exhibiting symptoms of fatigue.

Food allergies: food allergens cause several symptoms one of them including fatigue. Some allergies manifest physically e.g. through swelling while others do no show. Most patients with chronic fatigue may not realize that it is being caused by the foods they eat because the allergies are not physically manifested.

Nicotinamide Adenine Dinucleotide (NAD) Treatment

The fatigue experienced in chronic fatigue syndrome is as a result of declined energy levels in the body. NAD treatment is one the several ways of treating chronic fatigue as it is shown to boost energy levels in an individual. Nicotinamide adenine dinucleotide (NAD) is usually a molecule whose work is to react with the mitochondrial oxygen in order to produce energy required for body functions such as breathing, digestion and blood circulation among others. When the body lacks this essential energy, it means that energy production is affected leading to fatigue, anxiety, depression, muscle pains, memory impairment, insomnia, decreased concentration levels as well as other chronic conditions.

NAD is usually an active form of the B3 vitamin. When combined with hydrogen it becomes a coenzyme called NADH. The body uses hydrogen in combination with oxygen to generate energy. The carbohydrates, fats and proteins we take in our diets, have chemicals that are necessary for energy production. The NAD is then loaded with hydrogen and when it enters the mitochondria, it reacts with the oxygen present producing energy. Conditions such as stress and toxins end up inhibiting this process and energy is not produced resulting in fatigue.

Patients with chronic fatigue syndrome undergo NAD therapy in order for the body to actively generate energy. Research studies show that NAD is present in almost every type of food we consume. However, most of it is lost during preparation and cooking of food. The little that is left is broken down in the digestive system by acids present. The body therefore ends up not having enough of the molecule which is why a large number of the population suffers from chronic fatigue.

To learn more about chronic fatigue and its treatment, just visit www.awaremednetwork.com. Dr. Dalal Akoury will also provide you with more health and awareness tips. She has treated many patients suffering from chronic fatigue syndrome by use of NAD Therapy. You too can be part of this healing at AwareMed.

Chronic Fatigue and NAD Treatment

 

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How To Re-Energize The Mitochondria By Use Of Intravenous Therapy

How To Re-Energize The Mitochondria By Use Of Intravenous Therapy To Prepare For Easy Addiction Detoxification

Intravenous TherapyDamages and the dysfunctions in mitochondria is an important factor in a range of human diseases due to their influence in cell metabolism. Mitochondrial disorders often manifest in a number of ways such as neurological disorders, diabetes and endocrinopathy.

In other diseases, defects occur in nuclear genes leading to dysfunctions of the mitochondrial proteins. Diseases such as hereditary spastic paraplegia, Friedreich’ ataxia and Wilson’s disease also result because of this. These diseases are inherited as in the case to other genetic diseases.

Mitochondria are central to oxidative phosphorylation and plenty of metabolism in the body and are also involved in plenty of cell deaths. Mitochondrial dysfunction therefore contributes to a wide range of human illnesses. Many patients with disease of the mitochondria also have issues with their gastro-intestinal tract and this is treated by therapies through nutritional intake. Such like patients usually have weak immune systems and as such they are always in constant battle with numerous infections. History and research reveals that earlier intravenous nutrition consisted of protein and dextrose alone. Lipids were then later introduced and later removed due to complications, but this was later re-introduced again.

At the moment or rather current time, there are multiple options in intravenous therapy for nutrition. The pump options are such as Gemstar and even CADD. Obtaining nutrients orally or through the gastro-intestinal is usually the most effective, since this is always a more physiological process.

However, if this is not possible, the intravenous nutrition is done, in the form of intravenous hydration or through home parenteral nutrition. Parenteral nutrition involves providing the patient’s calories using an intravenous line that leads into the central circulatory system. Intravenous nutrition involves giving fluids and can be used as a medium of providing electrolytes and other additives.

Various factors are important in determining the kind of hydration that is ideal for a patient. The length of time the procedure takes as well as how and where the hydration happens are most often the main factors to consider.

Hydration is a major issue with people suffering from mitochondrial disease. For one to decide to start intravenous hydration he should keep in mind whether the treatment is long-term or for a short term. The kind of lines through which intravenous hydration is done are peripheral, PICC line, PortACath and tunnel catheters.

Peripheral is placing the intravenous lines in the hand or arm and for a short period of time, normally between three to five days. This method is not ideal for use at home because it requires a professional to do it and fewer nurses have such kind of professional training.

MitochondriaPICC is placed with the aid of an X-ray in the upper arm where the catheter goes directly into the central circulatory system. The site or area of insertion should be protected from infections by always keeping it dry.

PortACath is usually placed in the upper chest of the patient.in this type of line, the needle can be removed and the patient is allowed to swim or even shower.

Tunnel catheters are also usually in the upper chest and surgically removed .however, they can also be placed somewhere hidden. There is a risk of infection with this type of intravenous hydration.

Many patients are allergic to the substances involved and suffer from skin breakdown and are therefore more susceptible to infections. Also because of lower immunity, they are prone to infections. Furthermore, these patients also stand a higher risk of clotting. These treatment lines should be handled with care and fewer people. They should be thoroughly washed and items cleaned separately. The access points should be sanitized with alcohol prior to injection.

Some complications such as catheter occlusion caused by blood clotting occur, due to thrombotic clots. But there are medications that clear clots on the catheter.

Infections are normally common because of a component in blood that encourages growth of bacteria. This component is known as biofilm. The biggest threat to intravenous nutrition however is catheter related blood stream infections. This is treated by antibiotics, antibiotic locks and by changing of the central line.

Intravenous therapy is also a great way to get a high dose of vitamins, vital minerals and antioxidants into the circulatory system. Therefore, the nutrients are quickly introduced into the circulation and are delivered directly into the cellular space without having to go through the gastro-intestinal tract.

Many people notice improved immunity, higher energy levels and enhanced detoxification through therapies.

Intra venous nutrient therapy also provides higher doses as   compared to oral therapy.

Scientists have been studying the effects of higher doses of Vitamin C for quite a long time.

Vitamin C is essential as a water-soluble vitamin that is commonly also known as ascorbic acid.  The antioxidant effects of Vitamin C have been researched extensively to show positive and protective benefits against many ailments.

Myer’s Cocktail, AMP/NAD Energy Shots and MSM Infusions can also be used to boost the mitochondria

One may just feel a cold or a viral illness is coming on but once you have an intravenous cocktail that may well restore your health.

Whether you need help on balancing adrenals or you are an addict who is looking for a natural way of gradually recovering from an addiction, Awaremed Resource And Wellness Center is your perfect solution. You are free to call us, for more go to www.awaremednetwork.com

How To Re-Energize The Mitochondria By Use Of Intravenous Therapy To Prepare For Easy Addiction Detoxification

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Poly MVA And Addiction Treatment

Role of Poly MVA in Addiction Treatment

What is poly MVA?

This is a supplement which is prepared in a very special way. These supplements are obtained from blending variety of minerals, vitamins and some amino acids. These supplements are meant to give support to cellular energy production and also promote overall health. Studies which have been conducted to ascertain the use of poly MVA have shown that people who take the supplement not only do they feel overly well but also feel high energy level. Another advantage of using poly MVA has been that, it balances the pH levels in the body. This helps your body’s wellness in many ways. Poly MVA has also been known to get rid of some harmful compounds which are known to harm liver. This makes your liver remain free from the effects of these chemicals.

Poly MVA in Addiction Treatment

How does poly MVA work?

The working principles of poly MVA are based on mitochondria. The understanding of mitochondria and how it works is therefore important before one seeks to understand how poly MVA functions.

What is this mitochondrion then? How does it work? Mitochondria are sometimes referred to as the cell’s power plants. They are discrete structures of any cell, which function to generate energy for the cell. For any cell to remain healthy there must be sufficient and reliable supply of energy. During the production of this energy o molecular level, a compound which helps in the transfer of this energy within the cell is also stimulated. This chemical is called Adenosine 5;-triphosphate.

Whenever poly MVA is administered to a patient, it crosses the cell membrane and thus it conducts electrical current from the membrane itself to the mitochondria. These mitochondria as discussed earlier are structures within the cell itself that serves as for production of energy and respiration. Under normal circumstances, mitochondria possess properties of ability to redistribute the electrical charge throughout the cell to energize it as well as enhancing its activity. When mitochondria cannot perform this function, there is need for intervention, preferably with the poly MVA supplement which will intervene and ensure the mitochondrial functions are executed.

Can poly MVA be helpful in addiction recovery?

Poly MVA has actually proven to be helpful when administered to patients who are recovering from addiction. It is a fact that almost all the addictive substances will damage given parts of your body. The process of recovering from this addiction, must involve healing of the damaged parts or cells, for a complete and successful recovery to be realized.

One of the common damages caused by addiction from drugs is cell malfunction. When the cells malfunction, there is high likelihood that the patient will be a victim of a disease as a result. This is common with cancer, which is caused by death of cells as a result of malfunction.

When poly MVA is administered, it helps to ensure that the cells which malfunctioned are restored back to their functional state. This occurs through re-energizing of mitochondria, which are the power plants of the cells. Poly MVA provides mitochondria with energy and thus stimulating it to function well.

Some of the properties which make poly MVA helpful in recovery are:-

  • It plays an important role in helping the body to produce energy. This is as a result of re-energizing mitochondria, which is responsible for production of energy for the cells.
  • Poly MVA has also proven to support the liver in removing some harmful substances from the body. These chemical substances which would otherwise harm the liver are removed from the body. This has health benefits beyond recovery from addiction, since the patient remains free from liver damage related illnesses even after recovering from addiction.
  • Poly MVA also plays a vital role in preventing call damage. When cells are not supplied with sufficient energy, they will definitely get damaged. Poly MVA ensures that optimal conditions for proper functioning of the cells are maintained.
  • Another advantage of using poly MVA is that it helps the body in removing heavy metals from the blood streams. Many of the heavy metals are known to be toxic. Their presence in the body could have a serious health impact. These metals need to be removed from the blood streams since their transportation throughout the body would be toxic to many body organs. Poly MVA helps the body to get rid of such metals.

Poly MVA in Addiction Treatment

  • Poly MVA, when used as a supplement can act as a very powerful antioxidant and detoxificant. It neutralizes the negative effect of poisonous compounds in the body. This is an effect which can be very helpful for a person recovering from drug addiction. Many addictive drugs are known to leave a residual effect and thus usage of poly MVA would neutralize this effect.
  • It also prevents B-12 deficiency, which is related to mental breakdown in people of elderly age. Deficiency in this chemical result to decline or loss in memory.
  • Another important property of poly MVA is that it supports nerves and neurotransmitter functioning. Neurotransmitter is responsible for reward system, and its proper functioning results to one feeling healthy and in a good state.
  • Poly MVA has also been proven to support white blood cells function. White blood cells protect our bodies from diseases, and by supporting their function, poly MVA contributes to healthy living.
  • Another important role of poly MVA worthy mentioning is that it plays role to balance pH levels in our bodies. This help in maintaining oxygenation of cells and tissues.

Addiction treatment process is a serious treatment procedure and should only be carried out by professional who are certified and really understand what they do. At Awaremed Wellness and Resource center, we understand all steps and phases of addiction treatment. If you need help with any addiction treatment, call in and keep reading our blog

Role of Poly MVA in Addiction Treatment

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DCA As a Glycolitic Inhibitor

DCA  As a Glycolitic Inhibitor Helps In Fighting Cancer

DCAThe oncologist will tell you that finding a treatment that is effective in killing the cancer cells while safe on the healthy body cells was the biggest problem in the field of oncology. The cancerous cells just as much as the healthy cells need nutrients to continue living.  The oncologists plus other medical researchers have noted that the best way to treat cancer without affecting the healthy body cells is to deny them the nutrients supplies so that they can be starved to death. The cancer cells and the body cells require glucose from which they can make the ATP energy that they need to survive on. This made it hard to deny the cancer cells their nutrient supplies while leaving the healthy body cells nutrient supply unaffected. But this was in the past. Cancer researchers have found some existing differences between the survival mechanisms of the cancerous cells and the healthy body cells. Otto Warburg discovered that the cancerous cells depended entirely on the glucose to survive without which it could not live while the healthy body cells could make other sources of energy and continue living even when the sugar sources of energy were withdrawn. This discovery has led to more selective killing of the cancer cells without affecting the living body cells. The cancerous cells undergo increased glycolysis and rely on this pathway for generation of ATP energy as their sole source of energy for growth and survival but the healthy body cells are flexible to switch to other sources like fats.

Since the discovery by Warburg, oncologists have come up with different cancer therapies to help in killing the cancer cells effectively without hurting the healthy body cells. Overdependence of the cancer cell on the glycolitic pathway for generation of ATP energy as the sole source of survival has provided a great loophole through which the cancer cells can be selectively killed without affecting any other healthy cell by inhibiting glycolysis. To do this, glycolitic inhibitors must be used in order to weaken the cancer cells by blocking their nutrient supplies which is an anticancer itself thereby killing the cancer cells more effectively.

Cancer cells are characterized by increased glycolysis therefore when glycolitic inhibitors are used the cancer cells have no other ways of survival therefore they will die out of starvation. This approach has also been applauded in killing of cancer cells with mitochondrial defects that have become resistant to chemotherapy and radiation therapy drugs.

It may not be easy to understand the molecular and biochemical mechanisms that lead to increased aerobic glycolysis in the cancer cells, the metabolic repercussions of this increased glycolysis is very clear. The malignant cells become dependent or other addicted to the glycolysis pathway as the sole source of ATP energy. Researchers opine that the increased glycolysis in cancer cells may be caused by such factors as; hypoxia, oncogenic signals as well as mitochondrial dysfunction.

It is a known fact that the cancer cells need more energy to survive than the healthy cells. In glycolysis the ATP produced per glucose are only 2 which means the cancerous cells must use lots of glucose to survive unlike in the oxidative phosphorylation which generates more ATP energy per glucose the . Here 36 ATP are produced per glucose therefore small amount of glucose is needed for survival. So without glycolitic pathways the cancer cells are doomed.

In case of is glycolytic inhibition the healthy body cells will be able to adapt to other metabolic pathways to generate the ATP energy through the TCA cycle and oxidative phosphorylation in the mitochondria. The cancer cells however cannot adapt to other sources of ATP hence will die as they will not be able to live without another source of ATP energy. The healthy body cells will be able to adapt to new sources of energy like fatty acids and amino acids to produce metabolic intermediates channeled to the TCA cycle for ATP production through respiration. Glycolysis inhibition is therefore a clever way of killing the cancer cells without harm on the healthy body cells.

DCA is an effective glycolytic inhibitor

DCA works in very interesting ways in inhibiting glycolysis. It only leaves one option left for cancer cells to survive on- depending on other pathways as opposed to glycolysis. The cancer cells cannot do that hence they are killed. The healthy body cells can adapt to metabolic changes unlike the cancerous cells. The first way through which the body cells get energy is through glucose oxidation which happens in the mitochondria of every cell in the body and requires oxygen. Glucose respiration is the mostly utilized form of metabolism in the healthy cells. However in absence of oxygen the cells turn to glycolysis which takes place in the cell cytoplasm for energy generation. Glycolysis does not avail adequate ATP energy for normal cells; however it is the best for cancer cells. Glycolysis depends on sugar. This gives the healthy cell advantage as they have a backup plan in case the oxygen supply is interrupted. However to oxidize glucose there must be pyruvate. Pyruvate entry into the mitochondria is inhibited by an enzyme known as pyruvate dehydrogenase kinase (PDK). In case the PDK is strong then it will limit the transportation of pyruvate into the mitochondria and the healthy cells will have to depend on glycolysis even in presence of oxygen but incase its weak the pyruvate will be transported with ease to mitochondria even when the oxygen is low.

DCACancer cells have the most active PDK than the healthy cells and they are adapted to glycolysis. When PDK is weak then the cancer cells are disadvantaged and this is what the DCA does. It weakens PDK forcing the cancer cells to rely on glucose oxidation which does not favor them. Hence they will starve and die.

Dr. Dalal Akoury (MD) is an experienced integrative cancer doctor that has helped many cancer patients in their fight against the disease. She has worked hard not only in treating the disease but also in availing informational support to cancer patients at Awaremed which has become a place called home for many cancer patients. Call on her now and get help on cancer.

DCA As a Glycolitic Inhibitor Helps In Fighting Cancer

 

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