Tag Archives: dental stem cells

stem cell therapy

Stem cell therapy can restore function after stroke damage

Recently scientists discovered that a patient could recover, and his or her function can be restored after suffering stroke for a longer period. For this to happen, stem cells in his or her brain have to be stimulated.

Some scientists from UC-Irvine discovered that Transforming Growth Factor-Alpha often abbreviated as TGFa can activated adult stem cells that are in the affected area of the brain to differentiate, move through the brain and last bit not least, repair the damage caused by the stroke.

To prove this can happen, scientists tested a rat that was affected. The Transforming Growth Factor-alpha protein was then injected directly into its brain four weeks after the stroke damage. The recovery was 99%.

Darius Gleason who is a graduate student who was also working on the project mentioned that it is becoming clear that brain isn’t different from any other organ. We just assume that it is somehow superior given to what it can do. The brain is, without a doubt, the organ that decides what the body should do and what it shouldn’t.

Unlike many other organs, a damaged brain is more devastating, in fact, it means the end of your functioning as a human being. However, the latest findings have shown that the brain can indeed repair itself just like any other organ in the body if the stem cells are introduced into it.

A new study recently published that nasal administration of the Transforming Growth Factor-alpha can result in a recovery by 70%. The nasal passage is one of the non-invasive routs that is quite useful for this kind of therapy.


stem cell therapy

In the previous years, researchers from Germany proved that administering adult stem cells through the nose was one of the most effective methods. The new finding is proof that using a stimulating factor can also work best to stimulate differentiation of adult stem cells that are already there.

However, there are several trials still going on in Houston that involves infecting the stem cells into the bone marrow of the patients and their circulatory system. The cells have been seen to move to the area of the brain that is affected and immediately they reach there; they activate the repair process. There are still findings not yet confirmed; the existing results are more promising especially for future stroke patients.

The bottom line

A lot is going on in the stem cell world. The discovery of stem cells has opened the eyes of scientist to another level of medicine. Unlike the past, there is a hope that diseases such as cancer that were not curable in the past can now be cured. And now that it can work on the brain to restore functioning after stroke, it is becoming clear that it holds answers to many other fatal complications.


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stem cell therapy

Stem cell and wellness industry

Stem Cell has positively impacted both the wellness as well as health industry. Apart from its initially intended purpose, recent studies have shown that stem cell can also perform best as an anti-ageing ingredient.

To understand how stem cell therapy and wellness industry are connected, it is vital to be well acquainted with the meaning of cell culturing and how it works.

Understanding cell culturing works

Culturing can be simply defined as the ability of medical specialists to obtain and cultivate a single adult cell in a laboratory. The single cell is expected to turn into human adipose cells or fibroblast conditioned media. Many new cells can then be grown from the fibroblast’s progenitor cell that is often obtained from the adipose cells of the humans.

The result is a conditioned media which contain protein secretions from the cells. These proteins are then included in the serums commonly used by health as well as wellness industries around the globe.

Several industries have used the conditioned media of adult cell always to solve several degenerative related complications. Among the most common serum types is the anti-aging serum often intended to eliminate stretch marks, wrinkles, reduce scars as well as reverse several aging signs.

Use of this anti-ageing serum is considered useful by many wellness industries because most aging signs are related to the health of cells in the human body.


stem cell therapy

For instance, wrinkles are stimulated by the inelasticity in the cells. The anti-ageing serum works best to replicate new healthy cells as well as stimulate the regrowth of cells that in turn facilitates reduction of aging signs.

Apart from being among the best remedies for aging, serums that are derived from cell culturing have been manufactured to solve several health-related complications such as the formation of blood vessels, prevention hair loss as well as enabling the body to heal faster.

There is also a series of clinical tests that have been carried out to convey the use of serum that is derived from conditioned media. The findings didn’t prove the effectiveness of this type of serum, but there is some evidence that it is highly dependent on adult conditioned media.


Cell culturing, although not fully accepted by many ethically-minded researchers, has impacted both the wellness as well as the health industry.

Apart from bringing new effective serums into the market, it has also encouraged several studies intended to bring out the new approaches to the production of potentially useful anti-ageing solutions. It is apparent that the researchers are more into maximizing the benefits of cell culturing with an aim of improving the performance of medical industries.


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dental pulp stem cells

Understanding How Dental Pulp Stem Cells Use and Banking Works

Dental pulp can simply be defined as the soft living tissue that exists inside your tooth. These soft tissues contain stem cells that are known as DPSCs. Just like any other stem cells, DPSCs have the ability to become any cell in human body.

Among the best functional Dental Pulp Stem Cells can be obtained from the baby’s milk teeth either on the lower or the upper incisors and canines. Studies have shown that this kind of stem cells can also be found in the wisdom tooth of a young adult.

Dental Pulp Stem Cells can be likened to mesenchymal cells known to be quite beneficial in various treatments. These cells can differentiate to form different types of cells in the body that includes, osteoblasts, adipocytes as well as chondrocytes.

Potential Uses of Dental Pulp Stem Cells

Dental Pulp Stem cells are among the vital requirements in regenerative stem cell therapies of several degenerative related complications. They offer a variety of potential therapeutic applications that include.

  • Myocytes: Muscle tissue repair
  • Neuronal: Brain and nerve tissue regeneration
  • Adipocytes: Fat tissue generation
  • Chondrocytes: They can generate and regenerate cartilage vital for joint injuries and arthritis treatments.
  • Osteocytes: Generation of Bones

In summary, dental pulp stem cells have the ability to generate some structures in the body that include bone, cartilage, dental tissue and more.

Understanding Dental Pulp stems cell harvesting

Stem cell harvesting is simply a procedure that involves the collection, storage as well as the preservation of Dental Pulp Stem cells. To maintain their nature, DPSCs have to be frozen and kept inside a stem cell bank. This requires the use of cryopreservation technology that maintains the stem cell’s variability. Here is the procedure.

dental pulp stem cells

Stem Cell Harvesting Steps

  1. Collecting of the cells: Here a dentist will extract the tooth from the donor and store it in a kit. The dentist will then send to the facility to be processed.
  2. Separating the stem cells from the dental pulp: Here the stem cells will be obtained from the dental pulp by crushing the tooth to access the cells. The cells will then be checked for sterility as well as quality.
  3. Preservation of the stem cells: If the stem cells make it past the viability test they will be preserved cryogenically. The cells will be frozen at a temperature of -238 F.

Advantages of Dental Pulp Stem Cell Banking

  1. Dental Pulp Stem Cells banking period is wide. It will work best for kids aged between 5 to 12 years as well as the seniors whose wisdom tooth is to be extracted.
  2. The collection from the dental pulp is easy, quick, effective and painless and the best part has no risks.
  3. Dental Pulp Stem cells have no controversies surrounding their use unlike what we see with the embryonic stem cells.
  4. They have also proven to be interactive with biomaterials putting them among the best choices for tissue repair.

The bottom line

Currently, several debates are revolving around the procedure behind stem cell application. There are ethical issues that give the proponents a hard time explaining why the world needs it. Using Dental Pulp Stem cells, on the other hand, is simple, safe and the best part, free of ethical issues.


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