Tag Archives: Dopamine and addiction

Dopamine Rush

Pleasures registration brain and addiction

Pleasures registration brain

Pleasures registration brain and addiction. When drugs get access to the brain, there is bound to be serious health problems

Pleasures registration brain and addiction: Neurotransmitter dopamine

Among the functions of the brain is that of pleasures registration as and when they happen irrespective of their origin. It doesn’t matter whether they’re associated with a psychoactive drug, a monetary reward, a sexual encounter, or a satisfying meal. The fact is in the brain pleasurable principles has a distinct role of releasing the neurotransmitter dopamine in the nucleus accumbens, a cluster of nerve cells lying underneath the cerebral cortex. Dopamine release in the nucleus accumbens is so consistently tied with pleasure that neuroscientists refer to the region as the brain’s pleasure center.

All drugs of abuse, from nicotine to heroin, cause a particularly powerful surge of dopamine in the nucleus accumbens. The likelihood that the use of a drug or participation in a rewarding activity will lead to addiction is directly linked to the speed with which it promotes dopamine release, the intensity of that release, and the reliability of that release. Therefore addictive drugs provide a shortcut to the brain’s reward system by flooding the nucleus accumbens with dopamine. The hippocampus lays down memories of this rapid sense of satisfaction, and the amygdala creates a conditioned response to certain stimuli.

Brain pleasurable principle and drug addiction: Learning the process

Previously it was believed that an experience of pleasure alone was enough to compel people into consistent seeking of addictive elements or activities. However new research findings indicate that the situation may be more complicated. This is because dopamines are not only responsible for the experience of pleasure but are also playing a role in learning and memory which are the two key elements in the transition from liking something to being addicted to it. Currently, the philosophy about addiction is that dopamine interacts with another neurotransmitter, glutamate to take over the brain’s system of reward-related learning. Remember that this system has an important role in sustaining life because it links activities needed for human survival (such as eating and sex) with pleasure and reward.

Finally, it may interest you to note that the reward circuit in the brain may include areas involved with motivation and memory as well as with pleasure. Addictive substances and behaviors stimulate the same circuit and then overload it. And therefore repeated misuse of any addictive substances or behavior will cause nerve cells in the nucleus accumbens and the prefrontal cortex (the area of the brain involved in planning and executing tasks) to communicate in a way that couples liking something with wanting it, in turn driving us to go after it. That is, this process motivates us to take action to seek out the source of pleasure. This can be very unhealthy more so if the source of pleasure is drugs. Many often run to drugs for pleasure and as such, the prevalence of drug abuse is on the rise. We can choose individually and collectively to correct this by scheduling an appointment with doctor Dalal Akoury MD, who is a veteran addiction expert and also the founder of AWAREmed Health and Wellness Resource Center for help today.

Brain pleasurable principle and drug addiction: Neurotransmitter 





Dopamine impact in substance abuse

Dopamine impact

The distinction between substance abuse and addiction is often very confusing, nonetheless knowing the distinction marks the beginning of proper healing from the scourge of addiction

Dopamine impact in substance abuse: The brain reward center

Drug seeking and craving to the brain is very interesting more so when considering how the brain functions. It is true that the brain has evolved over time in a way that ensures human survival. And in fact, our brain’s reward system is part of that survival system. In many instances, we often experience an urgent need for food whenever we are starving and generally have a powerful desire for sex too. All these happens because of the dopamine impact. And according to doctor Dalal Akoury MD and founder of AWAREmed Health and Wellness Resource Center, the brain’s reward system rewards food and sex because they ensure our survival. Unfortunately, drugs of abuse operate within these reward systems which leads people to experience an urgent need or powerful desire for drugs or addictive activities.

The brain’s reward system has ensured our survival. You may not have known but food, water, and sex are some of the elements that activate the reward system. Therefore when the brain’s reward center is activated, it releases dopamine. Dopamine then creates a pleasing, enjoyable sensation which then motivates us into repeating these behaviors which are necessary for our survival. The reason why this is happening is because dopamine has rewarded us with a pleasurable feeling. Doctor Akoury recommends that from an evolutionary standpoint of view, it is very helpful to have a reward system that works. Like for instance, imagine that there is very little food and you’re wandering around looking for food. When you finally find something to eat, this triggers your reward system. This pleasing feeling (dopamine “reward”) will associate with whatever behavior that led you to that food. This causes you to want to repeat that behavior.

Moreover, the reward system is closely tied to emotional and subjective memories. If you were successful and found food in a particular place for instance, in the future you will want to look for food in the same location. This reward system increases the likelihood that you will be successful in finding food there the next time. This is because your brain chemicals are rewarding you with a pleasing sensation. It also helps you to remember how and where this pleasant feeling occurred.

Dopamine impact in substance abuse: The negatives of reward sensations

It will come to you as a surprise that the element that motives your survival is, unfortunately, the very same reward system that ensures your survival also rewards drug use. Doctor Akoury says that all addictive substances and activities will trigger the release of dopamine which rewards us with a pleasant sensation thereby succeeding in motivating us to continuously indulge in these harmful behaviors. It is nowadays common knowledge that peoples with addiction problems will do all it takes to get their drug of choice and in the same way, they continue with their addiction despite the harm it causes to themselves or their loved ones.

It is therefore very important to note that all these characteristic of addictive behaviors arise from the brain’s pleasure and rewards centers. Therefore seeking for lasting solutions becomes a must to do for all victims. This may not be a very popular thing owing to the addictiveness of some of these drugs, but nonetheless, it is the best option if you want to have a healthy life that is free from all sorts of addiction. You can schedule an appointment with doctor Dalal Akoury for the commencement of your journey to recovery.

Dopamine impact in substance abuse: The brain reward center







Dopamine reward principal

Dopamine reward principal

Dopamine reward principal. In fact, all addictive drugs and activities release varying amounts of dopamine into the nucleus accumbens with stimulant drugs like cocaine and methamphetamine releasing the most

Dopamine reward principal: Mesolimbic pathway

When the brain’s reward center is activated, it releases dopamine which then creating a pleasing, enjoyable sensation primarily to motivate individuals into repeating these behaviors necessary for survival. The reason why this is happening is because dopamine has rewarded us with a pleasurable feeling. That in itself is a testimony that dopamine reward principle (master) is the fueling the human survival. With that understanding of the purpose and functioning of the brain’s reward system. It would be important that we interrogate its (dopamine reward master) functions a little bit further.

Dopamine reward principal: Ventral tegmental area (VTA)

The circuit most associated with pleasure and reward is the mesolimbic pathway which is located in the brainstem. The objective of this area of the brain is primarily concerned with basic survival. Within the mesolimbic pathway is an area called the ventral tegmental area (VTA). The VTA projects to the nucleus accumbens (thought to be the reward center). The neurotransmitter most commonly linked with the mesolimbic system is dopamine. Many people consider dopamine to be the driving force behind the human pursuit of pleasure. The release of dopamine is a pleasurable sensation. The release of dopamine motivates us to repeat behaviors or activities that prompted this release. This system’s purpose was to promote survival by rewarding life-sustaining behaviors such eating and procreation.

Dopamine reward principal: Nucleus accumbens

All addictive drugs and activities release varying amounts of dopamine into the nucleus accumbens with stimulant drugs like cocaine and methamphetamine releasing the most. However, when it comes to drugs like alcohol or heroin, the brain’s own opiate system (endorphins) also gets involved. Doctor Akoury MD and founder of AWAREmed Health and Wellness Resource Center reiterates that even though different forms of addictions have different effects in the nucleus accumbens, they share one common denominator, that is, they all activate the reward system which in turn motivates us to repeat those behaviors, even though they may be harmful. Besides what we have discussed about the concepts of reward, pleasure, and craving together, it is however very important to appreciate that there is a distinction between pleasure-seeking and drug seeking. Note that pleasure-seeking is all about the pleasurable, rewarding aspect of addiction while drug-seeking refer to the craving aspect of addiction. Dopamine may be more involved in drug-seeking (craving) component of addiction. The opiate (endorphin), GABA, or glutamatergic systems may be more involved in a pleasure-seeking aspect of addiction too.

Finally, pleasure-seeking and drug-seeking (cravings) are interrelated, yet distinct. Research has established that natural rewards (food, water, sex) typically lessen their influence on the reward system over time. As a behavior occurs more often, dopamine levels tend to decrease in the process. Psychologists call this habituation. This makes sense. Once you’ve eaten enough food, you don’t need to be rewarded for eating more food. Then you would be eating too much, or too much of one type of food. Therefore everyone needs to take heed of keeping the brain free from all attacks be it from substances or otherwise. Talking to the experts at AWAREmed Health and Wellness Resource Center under the able leadership of doctor Dalal Akoury should be your starting point. Call us today to schedule that very important appointment today for the commencement of your journey to full recovery from your addiction.

Dopamine reward principal: Mesolimbic pathway




Dopamines on drug addiction effects


Dopamines on drug addiction effects and in fact dopamine levels variance and dopamine reward master. The neurotransmission and substance abuse needs immediate treatment

Dopamines on drug addiction effects: Drug addiction and the brain

Dopamine is an inhibitory neurotransmitter, meaning that when it finds its way to its receptor sites, it blocks the tendency of that neuron to fire. We have also noted previously that it is strongly associated with reward mechanisms in the brain. That aside, speaking to doctor Dalal Akoury MD, President, and founder of AWAREmed health center, new research on the brain is showing that addiction is a matter of memories, and recovery is a slow process in which the influence of those memories is diminished. That notwithstanding, further studies have also shown that addictive drugs stimulate a reward circuit in the brain. The circuit provides incentives for action by registering the value of important experiences. Rewarding experiences trigger the release of the brain chemical dopamine, telling the brain “do it again.” What makes permanent recovery difficult is the drug-induced change that creates lasting memories linking the drug to a pleasurable reward.

Dopamines on drug addiction effects: Brain circuits

Addiction involves many of the same brain circuits that govern learning and memory. Long-term memories are formed by the activity of brain substances called transcription factors. All perceived rewards, including drugs, increase the concentration of transcription factors. So repeatedly taking drugs can change the brain cells and make the memory of the pleasurable effects very strong. Even after transcription factor levels return to normal, addicts may remain hypersensitive to the drug and the cues that predict its presence. This can heighten the risk of relapse in addicts long after they stop taking the drug.

Knowing more about how addiction works in the brain has not yet given us any effective new treatments, but it has suggested new possibilities while providing a better understanding of how the available treatments work. The hardest job will be finding substances that lower the risk of addiction but do not interfere with responses to natural rewards. So far there is little evidence that any one type of therapy works better for addiction than another.

Dopamines on drug addiction effects: Brain Chemistry

It has been demonstrated times and again that drug addiction is a powerful force that can take control of the lives of users. In the past, addiction was thought to be a weakness of character or just misbehavior, but in recent decades research has increasingly found that addiction to drugs like cocaine, heroin, and methamphetamine is a matter of brain chemistry.

Experts at the National Institute on Drug Abuse, says that the way a brain becomes addicted to a drug is related to how a drug increases levels of the naturally-occurring neurotransmitter dopamine, which modulates the brain’s ability to perceive reward reinforcement. The pleasure sensation that the brain gets when dopamine levels are elevated creates the motivation for us to proactively perform actions that are indispensable to our survival for example eating or procreation. Dopamine is what conditions us to do the things we need to do. Having understood the power of addiction and what it can do to your health, it would be unwise to let drugs bring you down because of ignorance. Doctor Dalal Akoury founded this facility to help you have your life back and live it to the fullest. Waste no time and schedule an appointment with today for the commencement of your recovery process.

Dopamines on drug addiction effects: Drug addiction and the brain










Neurochemical reward and drug addiction effects

Neurochemical reward

Neurochemical reward and drug addiction effects on the brain may include certain pleasurable principle and that explains why the brain needs to be protected the most

Neurochemical reward and drug addiction effects: Addiction and the brain

Using addictive drugs floods the limbic brain with dopamine taking it up to as much as five or 10 times the normal level. With these levels elevated, the user’s brain begins to associate the drug with an outside neurochemical reward. Over time, by artificially raising the amount of dopamine our brains think is normal, the drugs create a need that only they can meet. Like for instance, when a drug produce increases in dopamine in these limbic areas of the brain, then your brain is going to understand that signal as something that is very reinforcing, and will learn it very fast so that the next time you get exposed to that stimuli, your brain already has learned that reinforcing instantly. Over time, the consistently high levels of dopamine create plastic changes to the brain, desensitizing neurons so that they are less affected by it, and decreasing the number of receptors. That leads to the process of addiction, wherein a person loses control and is left with an intense drive to compulsively take the drug.

According to experts the reason why dopamine-producing drugs are so addictive is that they have the ability to constantly fill a need for more dopamine. So a person may take a hit of cocaine, snort it, it increases dopamine, takes a second, it increases dopamine, third, fourth, fifth, sixth. So there’s never that decrease that ultimately leads to the satiety. Addiction has to do with the brain’s expectations. An emerging idea is that drugs basically hijack the brain’s normal computational enjoyment and reward mechanisms.

For example, let’s say you’re happy about a great chocolate ice cream and over time you learn to expect that the chocolate ice cream is really great and you have no more dopamine released in expectation of that when you receive it. Nevertheless, if you take an addictive drug you can never learn to expect it because the drug itself will release an extra kick of dopamine. And when that happens, the value of that drug keeps increasing because now you’re learning that wow my expectations were violated, therefore this must be much more valuable than what I thought before. So what ends up happening is that dopamine system gets hijacked by these drugs.

It must be noted that there are other components to addiction like genetics and age of exposure which is why not everyone who takes drugs becomes an addict. Approximately 50% of the vulnerability of a person to become addicted is genetically determined, and research indicates that if a person is exposed to drugs in early adolescence they are much more likely to become addicted than if they were exposed to the same drugs as an adult.

Neurochemical reward and drug addiction effects: Neurotransmitter dopamine

Doctor Dalal Akoury acknowledges that one of the key functions of the neurotransmitter dopamine is to create feelings of pleasure that our brains associate with necessary physiological actions like eating and procreating. We are driven to perform these vital functions because our brains are conditioned to expect the dopamine rush that accompanies them. Addictive drugs flood the brain with dopamine and condition us to expect artificially high levels of the neurotransmitter. Over time, the user’s brain requires more dopamine than it can naturally produce, and it becomes dependent on the drug, which never actually satisfies the need it, has created.

Finally, AWAREmed Health and Wellness Resource Center under the able leadership of Doctor Akoury is a facility run by experts headed by doctor Akoury, for proper care and healing of whatever kind of addiction and whatever the level of addiction you need caring experts who will focus on Neuroendocrine Restoration (NER) to reinstate normality through realization of the oneness of Spirit, Mind, and Body, Unifying the threesome. This kind of treatment can only be found at AWAREmed. Reach out for help and get your life back with real professionals.

Neurochemical reward and drug addiction effects: Addiction and the brain