Tag Archives: National Institutes of Health

When alcoholism and alcohol abuse features in the family

When alcoholism and alcohol abuse features in the family: Helping a loved one with alcoholism or alcohol abuse

When alcoholism and alcohol abuse features in the family

When alcoholism and alcohol abuse features in the family, careful attention must be taken to ensure that the consequences of its addiction is eliminated before it affects the family

You may be wondering how people who are struggling with alcoholism and alcohol abuse cope in their families. Probably you have never had anybody from your own family going through this kind of life situation. If you are such a person, then this article is meant for you. Remember that the problem of alcoholism and alcohol abuse is a global problem and you need to have all your facts right. Therefore to respond to your question “when alcoholism and alcohol abuse features in the family what do you do?” doctor Akoury states that if everyone could be this concern to the point of asking worthy questions like this in readiness of any eventuality, dealing with drug addiction, alcoholism and alcohol abuse could become much easier. Now back to the point if someone you love has a drinking problem, a lot of things may be going on in your mind.  Like for instance you may be struggling with a number of painful emotions, including shame, fear, anger, and self-blame. Some of these problems may be so overwhelming that it seems easier to ignore it and pretend that nothing is wrong because that appears to be the easy way of doing it. But whatever the decision you make, it must down on you that in the long run denying it (the existence of alcoholism and alcohol abuse) will not only be more damaging to you the direct victim, but also to other family members and the society in general.

That is why doctor Akoury made a decision to create a medical center (AWAREmed Health and Wellness Resource Center) whose main objective is to transform each individual’s life through increasing awareness about health and wellness and by empowering individuals to find their own inner healing power. Therefore when alcoholism and alcohol abuse features in the family, the very best thing you can do to salvage the situation is to seek audience with doctor Dalal Akoury immediately. Remember that Dr. Akoury’s practice focuses on personalized medicine through healthy lifestyle choices that deal with primary prevention and underlying causes instead of patching up symptoms. You can therefore reach out for her o telephone number 843 213 1480 to schedule for an appointment with her to get all the insight of all you need to do to offer the very best help to your loved ones.

When alcoholism and alcohol abuse features in the family: What not to do?

When you get to doctor Akoury’s office she will not just tell you what you need to do in order to help, but she will also impact in you all those things that you need NOT to do if you are to succeed in helping your loved ones. Some of the don’ts may include the following:

  • Don’t attempt to be hostile by way of punishment, threats, bribe, or preaching to the victim.
  • Don’t try to be a martyr. Avoid any emotional petitions that may only resuscitate the feelings of guilt and the compulsion to drink or use other drugs.
  • Don’t cover up, hide or make excuses for the alcoholic or problem drinker or shield them from the realistic consequences of their behavior.
  • In the process of helping don’t take over their responsibilities, leaving them with no sense of importance or dignity.
  • Don’t hide or dump bottles, throw out drugs, or shelter them from situations where alcohol is present.
  • Don’t argue with the person when they are impaired.
  • Don’t try to drink along with the problem drinker.
  • Above all, don’t feel guilty or responsible for another’s behavior.

Remember that dealing with a loved one’s alcohol problem can be an emotional rollercoaster. Therefore it’s vital that you take care of yourself and get the support you need. It’s also important to have people you can talk honestly and openly with about what you’re going through. A good place to start from is by joining a group such as Al-Anon, a free peer support group for families coping with alcoholism. Listening to others with the same challenges can be a tremendous source of comfort and support. You can also turn to trusted friends, a therapist, or people in your faith community.

You cannot force someone you love to stop abusing alcohol – Your intentions may be very good but remember that as much as you may want to help, and as hard as it is to watch, you cannot make someone stop drinking. The choice is up to them.

Don’t expect the person to stop drinking and stay sober without help – Your loved one will need treatment, support, and new coping skills to overcome a serious drinking problem.

Recovery is an ongoing process – Recovery is never a smooth road, it will require time, commitment and patience to sail through. Take note that an alcoholic will not magically become a different person once sober. And the problems that led to the alcohol abuse in the first place will have to be faced.

Admitting that there’s a serious problem can be painful for the whole family, not just the alcohol abuser. But all the same don’t be ashamed about anything because you’re not alone. Alcoholism and alcohol abuse affects millions of families, from every social class, race, and culture the most important thing is seeking for professional help from the experts at AWAREmed Health and Wellness Resource Center not just for the direct victims but also for the indirect victims too.

Finally dear reader when alcoholism and alcohol abuse features in the family, you must never panic. This is a treatable disease and the faster you seek for help the better for you and your family. Therefore take swift actions towards containing the problem by scheduling for an appointment with doctor Dalal Akoury one of the best known addiction professionals of our time. Upon scheduling for that appointment, she will in the most professional way evaluate your individual conditions before putting you in the right treatment program. So waste no more time and call her today.

When alcoholism and alcohol abuse features in the family: Helping a loved one with alcoholism or alcohol abuse

 

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Sex Addiction Stress, and Stress

Stress, Sex And Addiction: Roles Of Corticotrophin Releasing Factor, Oxytocin And Arginine- Vasopressin In Sex Addiction Stress.

Sex Addiction

Sex Addiction Stress

Stress sensitivity and sex are predictive factors for the development of neuropsychiatric conditions. it has been thought stresses are the sole cause for addiction but this isn’t true since triggers can also cause relapse to drug use. Sex Addiction Stress and stress involve similar pathways.

The development and clinical course of addiction-related disorders do appear to involve neuroadaptations within neurocircuitries that modulate stress responses and are influenced by several neuropeptides. These include corticotropin-releasing factor, the prototypic member of this class, as well as oxytocin and arginine-vasopressin that play important roles in affiliative behaviors. Interestingly, these peptides function to balance emotional behavior, with sexual dimorphism in the oxytocin/arginine-vasopressin systems, a fact that might play an important role in the differential responses of women and men to stressful stimuli and the specific sex-based prevalence of certain addictive disorders.

Stress and Sex Addiction Stress

Stress generally is defined as any stimulus that challenges physiological homeostasis—that is, which alters the balance or equilibrium of the normal physiological state of the organism.

Individuals exposed to chronic stress exhibit a higher propensity to become addicts. Stress-induced relapse is also higher in addicts. In general, there is a higher prevalence of addiction in patients diagnosed with anxiety disorders and depression. Additionally, childhood trauma is associated with increased vulnerability to addiction. Exposure to high peer deviance in childhood and adolescence is among the strongest known risk factors for drug use and drug abuse. Interestingly, a very recent study has found that individuals with increased risks of drug addiction because of parental divorce or genetic liability are more sensitive to the pathogenic effects of peer deviance.

Stress and addiction are interconnected in several ways. For example, stressful life events may predispose individuals to engage in addictive behavior or relapse.

Sex Addiction Stress

Epidemiological studies have observed significant sex- specific differences among patients suffering from addiction and other neuropsychiatric disorders. The onset, severity, clinical course, and treatment response of anxiety disorders also differ significantly in women compared to men. Importantly, the sex bias in neuropsychiatric disorders, including post- traumatic stress disorder (PTSD), remains even after adjusting for the type of trauma, pre-existing psychiatric disorders, and sex differences in reporting. Several studies have found increased prevalence of depression in women. Similar sex differences exist for addictive disorders. For example, more adult males abuse addictive drugs than females across most drug classes, including alcohol, psychostimulants, and narcotics. However, women develop addiction more quickly. There are also critical differences in the way that illicit substances affect the two sexes.

Men and women also show different propensities to relapse, and are differentially affected by triggers for relapse to drug taking, putting women at greater risk for repeated relapses despite the higher prevalence of drug abuse in men. Interestingly, once the addiction cycle resumes, women show longer periods of drug use before their next quit attempt.

The sex differences may also be a result of hormonal and neural differences between men and women in relationship to their response to the addictive behavior.

Corticotropin-releasing factor and  Sex addiction Stress.

CRF is a 41-amino acid-containing neuropeptide. CRF orchestrates the stress response by acting at the level of the pituitary to initiate the HPA axis response to stress, as well as centrally to modulate limbic and brain monoamine systems that are important in autonomic and behavioral components of the stress response. CRF causes its effects by stimulation of corticotropin-releasing factor 1 receptor (CRF1R) and CRF2R, and displays an 18-fold greater affinity for CRF1R than CRF2R.

Physiological responses to stress involve the release of CRF from the paraventricular nucleus (PVN) of the hypothalamus, followed by stimulation of ACTH release from the anterior pituitary. ACTH, in turn, stimulates the secretion of cortisol/corticosterone from the adrenal glands. In addition, CRF has an extensive extrahypothalamic influence across the corticostriatal-limbic regions, and plays a critical role in modulating subjective and behavioral stress responses. Central catecholamines, particularly noradrenaline and dopamine, are involved in modulating brain motivational pathways that are important in regulating distress, exerting cognitive and behavioral control, and tempering behavioral and cognitive responses critical for adaptation and homeostasis. The hypothalamic and extrahypothalamic CRF pathways and central catecholamines target brain motivational path- ways to critically affect adaptive and homeostatic processes. CRF dysregulation has been linked to the pathophysiology of mood and anxiety disorders. During stress, release of limbic CRF can modulate monoamine systems that have been implicated in mood and cognition. Although activation of both the HPA axis and central monoaminergic systems by CRF during acute stress is adaptive, the inappropriate or persistent activation of these systems can have adverse consequences leading to psychopathology.

Oxytocin and arginine-vasopressin in Sex addiction Stress

Sex addiction and stress

Sex addiction Stress and stress

Cells originating in the PVN have specific pathways that efficiently deliver OXY to other structures in the brain including the amygdala, BNST, septum, hippocampus, and NAc. OXY released by peripheral organs or by the posterior pituitary does not readily cross the blood–brain barrier, with only 1–2% crossing. In disparity, the local expression of OXY receptors is highly variable and explains differences in social attachment within and between species. OXY exerts anxiolytic and anti- depressive effects in various models.

OXY, in collaboration with hormone dopamine, is vital for pairing and bonding in prairie voles. When OXY is infused into the VTA, it increases dopaminergic activity in the NAc, and stimulation of oxytocinergic projections within the VTA increases extracellular DA within the NAc while concurrently inducing penile erection. OXY-induced dopaminergic release within the meso- limbic DA system may impact the attribution of incentive salience to a variety of social stimuli and ultimately influence an organism’s drive towards such objects thus causing addiction.

Sex Addiction Stress is a menace that should be fought by all means that is why we at Integrative Addiction Institute are committed to availing help to addicts and offering training to Health care providers in Integrative Addiction. Call on Dr. Dalal Akoury (MD) today for assistance.

Stress And Sex Addiction Stress: Roles Of Corticotrophin Releasing Factor, Oxytocin And Arginine- Vasopressin In Sex Addiction.

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Unique Properties of Stem Cells

What Are The Unique Properties Of All Stem Cells?

Stem CellsThe stem cells have been hailed for their efficacy in treatment of certain diseases especially those that are degenerative in nature like the Parkinson’s disease, osteoarthritis and even the Huntington’s disease. To accomplish all its medicinal capabilities the stem cells must have certain properties that are not present in other body cells. They therefore differ from other cells in the body. The stem cells are available majorly in the bone marrows and the adipose tissues but can also be harvested from placentas after a safe delivery. The stem cells have three general properties regardless of their source. These properties are; they are capable of dividing and renewing themselves for long periods; they are unspecialized; and they can give rise to specialized cell types. It is these distinct characteristics of the stem cells that make them effective in treatment of degenerative diseases.

The other cells found in the body like the nerve cells, the muscle cells and the blood cells are not able to replicate themselves unlike the stem cells that are able to proliferate after long periods of time. Typically, a starting population of stem cells that proliferates for many months in the laboratory can yield millions of cells. What is more is that the daughter cells are capable of long term self-renewal giving rise to more unspecialized cells.

Despite the vast research that has been done on the stem cells and their ability to treat certain diseases there are some information that are still required which we can only hope that researchers will one day find an answer to. These questions are as follows:

  • Scientists are trying to understand two fundamental properties of stem cells that relate to their long-term self-renewal:
  • Why can embryonic stem cells proliferate for a year or more in the laboratory without differentiating, but most adult stem cells cannot; and
  • What are the factors in living organisms that normally regulate stem cell proliferation and self-renewal?

When these answers are addressed there will be a valid explanation to how cell proliferation is regulated during normal embryonic development or during the abnormal cell division that leads to cancer. Such information would also enable scientists to grow embryonic and non-embryonic stem cells more efficiently in the laboratory to help in treatment of diseases.

The stem cells are unspecialized

Stem cells remain unspecialized even after long hours in the laboratory after getting harvested. The scientists have spent years of research trying to find out factors that make the stem cells unspecialized and differentiating into different cell types. It took two decades to learn how to grow human embryonic stem cells in the laboratory following the development of conditions for growing mouse stem cells. In a similar manner the scientists must first understand the signals that enable adult stem cell population to proliferate and remain unspecialized before they will be able to grow large numbers of unspecialized adult stem cells in the laboratory for medicinal use.

The stem cells are not specialized and hence are not able to perform specific functions. Unlike heart muscle cells, the stem cells are not able to pump blood through the body, they can neither carry oxygen molecules through the bloodstream like red blood cells nor can they kill pathogens like the white blood cells but they can give rise to more of all these cells; they can form bone, heart muscle cells, blood cells and even nerve cells. So they are then unspecialized cells that have the unique ability to give rise to specialized and more vital functional specialized cells.

Stem cellsThe process through which undifferentiated stem cells give rise to specialized cells is known as differentiation. It is through this process of differentiation that the stem cells become even more specialized. Scientists are just beginning to understand the signals inside and outside cells that trigger each step of the differentiation process. The internal signals are controlled by a cell’s genes, which are interspersed across long strands of DNA and carry coded instructions for all cellular structures and functions. In contrast, the external signals for cell differentiation include chemicals secreted by other cells, physical contact with neighboring cells, and certain molecules in the microenvironment. The interaction of signals during differentiation causes the cell’s DNA to acquire epigenetic marks that restrict DNA expression in the cell and can be passed on through cell division giving rise to more specialized cells.

There are however some questions that should be addressed and these may include; Are the internal and external signals for cell differentiation similar for all kinds of stem cells? Can specific sets of signals be identified that promote differentiation into specific cell types? Finding answers to these questions may help scientists to find new ways to control stem cell differentiation in the laboratory, thereby growing cells or tissues that can be used for specific purposes such as cell-based therapies or drug screening.

Integrative Addiction Conference 2015

With these distinct characteristics of the stem cells especially their ability to give rise to different specialized cell types, the stem cells are a cutting edge to treatment of diseases. Degenerative diseases have debilitated many people but it is treatable. Dr. Dalal Akoury (MD) is an expert in integrative medicine and a founder of AWAREmed Health and Wellness Center located at Myrtle Beach South Caroline. Visit her for more information on most lifestyle diseases.

What Are The Unique Properties Of All Stem Cells?

 

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Vitamin D for Fibromyalgia

The Use of Vitamin D for Fibromyalgia

Vitamin DAs mentioned in an earlier written article, Fibromyalgia is a disorder characterized by widespread muscle pain, joint stiffness, and fatigue. The condition is chronic but pain comes and goes and moves about the body. The cause of this disorder is unknown and therefore it is often misdiagnosed or unrecognized and is most of the times complicated by anxiety and mood disorders. this is a common disorder that according to the American College of Rheumatology diagnosis criteria affects about 3-5% of women, most of whom are between ages 20 and 50, but only 0.5- 1.6% of men. This disease is more common in adults than in children but it affects women more than men. This disease is debilitating and is not easily cured. The patients also suffer a lot of pain and use of drugs to manage this pain can result in problems of addiction and dependence on the pain management drugs. The quest to find effective treatment for this disease has led to many researchers doing lots of research on possible treatments or therapies that can be utilized to help mitigate on the adverse symptoms of fibromyalgia. One of these possible alternatives that have been unearthed by past researchers is the use of vitamin D.

Vitamin D being associated with fibromyalgia should not be a surprising discovery as vitamin D has been known to be a strengthening factor to bones especially during early life in a person’s life. Practice such as basking in the sun is common in most parts of the world with biggest benefits being that the sun helps in activating vitamin D that hence works to strengthen bones. Deficiency of vitamin D in children is often characterized by bone deformities such as bowed legs.

Researchers from Harvard School of Public Health (HSPH) in Boston studied patients with fibromyalgia and multiple sclerosis, they found that the patients who had levels of vitamin D fared much better than those with lower levels. The result of this study was published in JAMA Neurology.

During this study the vitamin D levels of 465 participants were examined. The patients were then followed over a five year period as part of a study to monitor patients given Betaseron which is an FDA-approved multiple sclerosis drug. They discovered that increasing vitamin D levels within the first 12 months of drug therapy resulted in a 57 percent lower risk of relapse. According to the study, patients with low vitamin D levels early on in the course of the disease had a higher risk factor for long-term multiple sclerosis progression. However this study did not show whether multiple sclerosis causes a fall in the level of vitamin D in the body or whether low vitamin D plays a role in aggravating the disease. however the lead author of the study expressed a belief that the disease is most likely worsened by a fall in the levels of vitamin D. the lead author Alberto Ascherio, D.P.H., M.D., a professor of epidemiology and nutrition at HSPH said, “Most likely, disease activity is exacerbated by low vitamin D levels,” based on what they found in the study when interviewed by Healthline.

Vitamin D supplementation for fibromyalgia

The research on the effects of vitamin D on patients suffering from fibromyalgia was done in Vienna, Austria by Dr. Florian Wepner, of Orthopedic Hospital Vienna Speising. This research showed that higher vitamin D levels are associated to lower levels of pain and fatigue in fibromyalgia patients. In this study there were thirty participants who were all suffering from fibromyalgia. The thirty participants were divided into two groups. One group received vitamin D supplements while the other group was put on a placebo treatment. The researchers noticed that the patients who were put on vitamin D supplements had shown significant reduction in both pain and fatigue symptoms.

According to the findings of this study it can be shown that supplementing vitamin D can help alleviate the suffering of pain that patients suffering from fibromyalgia have to put up with. However the study lead investigator Wepner, M.D advised that fibromyalgia is a very complex condition that cannot only be explained by vitamin D deficiency alone.

Vitamin D“[Vitamin D] may be regarded as a relatively safe and economical treatment and an extremely cost-effective alternative or adjunct to expensive pharmacological treatment,” Wepner said in a journal news release.

Apparently, Dr. Wepner is not the only person that has promoted Vitamin D supplementation as a viable therapy for those suffering from fibromyalgia. Another doctor Dr. Kiran Patel has endorsed the same thought. Dr. Kiran is a pain medicine specialist at Lenox Hill Hospital in New York City and often deals with fibromyalgia, he said, “Fibromyalgia patients and those with chronic pain should certainly have their vitamin D blood levels checked and, if low, consider supplementation under the guidance of a physician,”

It’s good to bask in the sun

Despite the failure of this research to show the link between vitamin D and fibromyalgia or better yet the mechanism by which vitamin D helps mitigate on the symptoms of the disease, the benefits of vitamin D supplements have been seen and therefore it is good to maintain healthy levels of vitamin D for overall health purposes. According to the National Institutes of Health (NIH), for people ages nine and up, the safe, maximum intake level is 4,000 IU of vitamin D per day. This level of vitamin D can be enough to keep you on the safety levels of vitamin D.

Finally, fibromyalgia is a serious threat that has no known treatment. There is need to come up with safer yet effective alternatives of treating it. This is why here at AWAREmed Health and Wellness Resource Center we are committed to availing the best integrative approaches to treatment of diseases. Visit as at Myrtle Beach, South Carolina where Dr. Dalal Akoury (MD) will be of help.

The Use of Vitamin D for Fibromyalgia

 

 

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Alcohol Abuse and Colorectal Cancer

Research Shows Alcohol Abuse Can Cause Colorectal Cancer

colorectal cancerIn the past few articles we looked into the effects of alcohol abuse in relation to initiating some cancers. Alcohol abuse has been linked to different cancers and this may be because of alcohol’s general effects on the body which includes the following;

Alcohol generates reactive oxygen species. These are chemically reactive molecules that contain oxygen which can damage DNA, proteins, and lipids through the process known as oxidation.

Alcohol also breaks down ethanol present in alcoholic drinks to acetaldehyde, which is a toxic chemical and a probable human carcinogen. This substance is toxic enough to damage both DNA and the genetic materials that make up the genes and this may cause mutation which causes cancer.

Alcohol also impairs the body’s own ability to metabolize and absorb a variety of nutrients that may be associated with a reduction in cancer risk, including vitamin A; nutrients in the vitamin B complex, such as folate; vitamin C; vitamin D; vitamin E; and carotenoids. Absence of these nutrients escalates the risk of cancer. It is also believed to increase the levels of estrogen hormone which is also associated with increased cancer risks.

Alcoholic drinks are also made up of very harmful contents which are mostly introduced during production. These may include nitrosamines, asbestos fibers, phenols, and hydrocarbons which may increase cancer risks.

Colorectal cancer

As the name suggests, colorectal cancer refers to cancers that affect the colon and the rectum. Colon cancer is cancer of the colon, which is at the lower part of the digestive system. On the other hand, rectal cancer is cancer of the rectum which is part of the last inches of the colon. Together these two cancers can be referred to as colorectal cancers. In the colon cancer may begin as small lumps that are non-cancerous clumps of cells known as adenomatous polyps, however these polyps will grow into cancerous cells. At the beginning these polyps will not show any symptom associated with cancer and this may even pose a greater health challenge, therefore it is important to have yourself screened regularly for colorectal cancer. There are several cancers of the colon and rectum but adenocarcinomas are the dominant cancer type constituting up to 95 percent of colorectal cancer but there are other rare types of tumors that are also equally dangerous.

Signs and symptoms of colon cancer

Just like any other disease there are indicators that you may be suffering from colorectal cancers. These signs and symptoms may include;

  • Persistent abdominal discomfort, such as cramps, gas or pain
  • A feeling that your bowel doesn’t empty completely
  • Weakness or fatigue
  • Unexplained weight loss
  • Constipation
  • Diarrhea
  • A change in consistency of passing stool
  • Rectal bleeding or blood in your stool

These symptoms though unpleasant may help you to know your status in relation to colorectal cancers and help you seek treatment in good time. However these symptoms may not show at early stages making it hard for colorectal cancer to be detected early. It is therefore advisable to go for screening to help with early treatment. If you notice any symptoms of colon cancer, such as blood in your stool or a persistent change in bowel habits the best you can do is to seek medical help.

Alcohol linked to colorectal cancer

Excessive alcohol consumption has been regarded as a risk factor for developing colorectal adenomas. In a study aimed to investigate the influence of excessive alcohol consumption on the occurrence of colorectal cancer among patients with at least one colonic adenoma done by M Bardou, S Montembault, V Giraud, A Balian, E Borotto, C Houdayer, F Capron, J-C Chaput and S Naveau it was found that In patients with at least one colorectal adenoma, excessive alcohol consumption increases the likelihood of developing high risk adenomas or colorectal cancer. In this study the participants were divided into three groups. All had at least one colorectal adenoma. The first group consisted of 401 heavy drinkers; the second group consisted of 152 patients suffering from irritable bowel syndrome (IBS) while the third group consisted of 108 patients with a family history (FH) of colorectal adenoma or cancer. For this study exclusive criteria were anemia, haematochezia, personal history of colorectal adenoma or cancer, and for groups heavy drinking and IBS a family history of colorectal adenoma and/or cancer.

colorectal cancerThis is not the first study to show this relation between alcohol abuse and colorectal cancer. This relation between alcohol consumption and risk of developing colorectal adenomas has been demonstrated previously by several authors. In a research it was found that the risk of polyps was increased three times for drinkers who did not smoke and 12 times for both drinkers and smokers compared with the risk of total abstainers. Naveau et al found that alcoholism and cirrhosis were two independent risk factors for colorectal adenomatous polyps after successive adjustments for sex, age, smoking, and serum cholesterol levels.

Alcohol addiction is a vice that should be fought by all means that is why we at AWAREmed Health and Wellness Resource Center are committed to availing help to addicts and offering them a place to call home. We offer NER Treatment and Amino acid therapy that are the most effective approaches to addiction treatment and recovery. You call on Dr. Dalal Akoury (MD) today and begin your journey to victory against addiction.

Alcohol Abuse and Colorectal Cancer

 

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