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Fetal Cells: Enhanced Efficiency And Effectiveness For Wound Healing.

Fetal Cells: Enhanced Efficiency And Effectiveness For Wound Healing

“Extensive burns and full thickness skin wounds can be devastating to patients, even when treated. There are an estimated 500,000 burns treated in the United States each year. The overall mortality rate for burn injury was 4.9 % between 1998 and 2007 and medical costs for burn treatments approach $2 billion per year,” Owan TE, Hodge D.O., Herges R.M, et al. (2006).

These statistics could as well be over 11 million injuries per year as claimed by some medical reports. Other than burns, full-thickness chronic wounds also claims a large number of patients and despite technological development of therapeutic approaches, healing rates remain way below 50 % of success.

Patients with the non-healing chronic wounds are as well estimated at about 7 million per year in the US alone. Yearly costs on the other hand continue to rise, the figure is currently approaching $25 billion. Patient survival is reportedly inversely proportional to the amount of time required to recover from such a chronic wound and to stabilize.

wound-healing

Those with severe burns of between or more than 15–20 % total their body surface area are also likely to go into shock without rapid treatment. In addition, without sufficient and or rapid fluid resuscitation, patient conditions deteriorate and mortality rates increase steeply.

Inadequate therapeutic programs often result in long-term patient complications including open wounds, prominent scars, prolonged pain, high temperature sensitivity, loss of feeling to touch and or itching.

Patients who suffer from such burns and or chronic wounds benefit from prompt treatments that result in appropriate closure and or protection of the wounds. Burn patients in particular, who receive delayed treatments, are usually subject to prolonged therapeutic care that has long-term negative physiological side effects.

Recent medical advancements have been made to handle wound healing; however, the generally accepted and practiced treatment approach still remains an autologous split-thickness skin graft. This involves extracting a piece of skin with the goal of removing stem cells from a minor surgical site on the patient’s body, stretching the skin, and re-applying the graft on the burn or chronic wound.

Stem cells are unspecialized cells in the body that majorly bear two specific characteristics. They have the capacity to replicate themselves indefinitely and have the ability to replace and or repair nearly all body tissues as directed.

Stem cells extracted from the amniotic fluid, (AFS) are reportedly a very rich cell source for use in regenerative therapy due to their high proliferation capacity, immune-modulatory activity and multipotency.

AFS also have the capacity to modulate inflammatory responses and secrete therapeutic cytokines. Because of these characteristics, AFS cells have been explored for treatments in wound healing and skin regeneration among similar therapeutic care.

These attempts have over time been backed by relevant scientific studies that increasingly indicate AFS cells are effective in accelerating healing of skin in embryonic environments and more recently in treating wounds in adults. More scientific evidence also points to the fact delivered cells are often temporary, that is, do not permanently integrate into final skin tissue.

Instead, they hide a portfolio of effective growth factors very vital to the skin regeneration and angiogenesis, suggesting a trophic ability of enhancing skin and or wound healing.

These initial pieces of scientific studies suggest delivery of AFS cells have the potential to be an effective cell treatment for enabling wound healing and should be considered for clinical trials and use in treating skin wounds in patients.

While this treatment indicates the ability to yield a reasonably good therapeutic outcome, if the wound is extensive, the number and size of donor sites may be limited, making autographs difficult to use in cases that require rapid and or aggressive measures to save the wounded patient’s life.

Alternatively, allografts may be used but the option suffers a critical need of immuno-suppressive drugs so as to prevent body immune rejection of the graft. This limitation has thus caused the creation of noncellular dermal substitutes, which most often comprises a polymeric scaffold.

They include skin regeneration template and Biobrane among others. Even though such polymeric scaffolds result in improved wound healing, they are costly to produce and more often result in relatively poor temporary outcomes.

Recent developments in tissue engineering have also led to more complex biological skin parallels that may yield more suitable alternative wound care options for patients. These include: cellularized graft-like products such as dermagraft, Apligraf (Organogenesis), and TransCyte, (Advanced BioHealing) among others.

The products are commonly polymer scaffold patches that are planted with human fibroblasts and cultured in vitro prior to their application. Unfortunately, these grafts are also expensive to produce, and as allografts, can suffer from the same immunological setbacks mentioned earlier.

Intergrative addiction Conference

This topic can go on and on. It is actually very interesting but it would not be possible to include everything in one article. However more information can be found at www.awaremednetwork.com. Dr. Dalal Akoury M.D., M.P.H., who is also a family physician and has many years of experience in integrative medicine will be of great assistance.

Also, do not miss an opportunity to learn and interact with various professionals during this year’s Integrative Addiction. For more information about the upcoming conference, visit http://www.integrativeaddiction2015.com. The conference will also deliver unique approaches to telling symptoms of addiction and how to assist patients of addiction.

Fetal Cells: Enhanced Efficiency And Effectiveness For Wound Healing.

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Pros and Cons of Suboxone

Problems with suboxone treatment, pros and cons of suboxone therapy

Suboxone

There has been an increase in prescription of opioid painkillers in the US, this phenomenon got me worried and backed up by a recent study that verified that the use of safer alternatives to pain management has been on the decline.

In recent years there has been a growing awareness in the medical community about the pervasiveness of pain. This awareness has corresponded to a sharp increase in the use of opioids and abuse with so many people involved in the use opioids for non-medical purposes.

One of the biggest disasters associated with this tremendous use of opioid painkillers is their potential to cause addiction.

Addiction to any drug substance be it medicinal or not is a very serious issue with extremely adverse socio-economic impacts in human populations all over the world. The move to try and help addicts recover from this societal demon is thus a noble one. Many addiction treatment centers have been set up in line with this move. Different medications are today in use in the world over and research is still ongoing with the aim of developing the most effective medication for addiction treatment. One such drug being used today in addiction treatment is suboxone.

What is suboxone?

Suboxone is a brand name for a prescription medication that is a combination of two drugs; buprenorphine and naloxone. Buprenorphine belongs to a class of drugs called opioid partial agonists which help relieve symptoms of opiate withdrawal. Naloxone on the other hand is belongs to a class of drugs called opioid antagonists which reverse the effects of narcotics. one of the most powerful narcotics isbuprenorphine is a narcotic, it is so powerful yet it has a potential o be addictive. it was approved for treatment of opioid addiction in 2002 in the United States.

This drug can be combined with naloxone to make Suboxone and be used to help addicts to fight opioids like vicodin, heroin, OxyContin, and hydrocodone. Naloxone has ability to block opioid receptors in the brain and trigger sudden withdrawal symptoms when injected. For treatment, Naloxone is added as deterrent to prevent addicts from injecting Suboxone. When taken as a pill, naloxone is not absorbed into the body.

Problems with suboxone therapy

When it was first released in 2002, suboxone was hailed as a major advance over methadone. But millions of but later there were millions of literature critiquing the use of this drug as it has faults as were thought earlier.

One of the biggest challenges associated with suboxone treatment is its being overprescribed and misused.

Over three million Americans with opioid dependence have been treated with Suboxone. This drug has been successfully used to help addicts but it has high potential of being abused.

A report by the Substance Abuse and Mental Health Services Administration (SAMHSA) found a ten-fold increase in the number of emergency room visits involving buprenorphine. Slightly over half of the 30,000 hospitalizations in 2010 were for misuse and abuse of buprenorphine.

How many died from buprenorphine overdoses is unknown, because medical examiners and coroners do not routinely test for the drug.

For a drug addict, the most uncomfortable, painful problem of their addiction is withdrawal. If they can somehow control their urge to delve back into the drug and endure the side effects of withdrawal, then they can successfully complete their addiction recovery and gain their freedom from use of drugs.

Suboxone is so popular with addicts that it has turned into a street drug – to be bartered or exchanged for money, heroin or other illegal drugs. According to one estimate, about half of the buprenorphine obtained through legitimate prescriptions is either being diverted or used illicitly.

Drug makers are well aware of the potential for misuse and abuse. Orexo, the maker of menthol flavored Zubsolv, is selling the tablets in single dose “blister” packaging designed to reduce accidental use by kids. Another maker, Reckitt-Benckiser took its Suboxone tablets off the U.S. market and currently sells Suboxone in individually wrapped film strips. However experts have it that no amount of preparation and packaging can outsmart a determined drug abuser.

The potential for abuse and diversion is however not reason enough to call for a stop in treating addicts with buprenorphine, according to a commentary published in the journal JAMA Internal Medicine that calls for a “balanced approach” to the drug.

The other major challenge associated with suboxone treatment is that it is causing its own epidemic of addiction. Patients undergoing suboxone treatment could overtime get addicted to the drug and show withdrawal symptoms when they try to get off its use.

Advantages of suboxone

One of the primary advantages of suboxone for addiction treatment is the fact that buprenorphine’s partial agonist quality prevents it from triggering respiratory depression -and thus overdoses.

Its other advantages include:

  • It isn’t met with stigma as with methadone.
  • It can often get to a stabilized dose within the first or second day.
  • It has a better safety profile.
  • It may be easier to come off than methadone.
  • It is longer acting than methadone so it may not require daily dosing.
  • Its side effects are less than those of methadone.

 

SuboxoneDisadvantages of suboxone therapy

Though suboxone is considered an advance in addiction treatment over methadone, it has its disadvantages. Some of these disadvantages include:

  • It may fail to fully satisfy cravings or inhibit withdrawal symptoms for those with high tolerance.
  • Dose adjustments may b more difficult.
  • It is also likely to cause a precipitated withdrawal.

Addiction is a societal menace for which support is required in fighting. That’s why we at AWAREmed Health and Wellness Resource Center are committed to availing help to addicts and offering them a place to call home. It matters not what kind of addiction you are wrestling with, just call on Dr. Dalal Akoury (MD) today and begin your journey to victory against addiction.

Problems with suboxone treatment, pros and cons of suboxone therapy

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Heroin Use on the Rise despite Its High Cost of Treatment

 Heroin on the Rise despite its High Cost of Treatment

Contrary to the common rule of demand and supply that the use of a product will be high when its price is at the lowest, heroin use has been on the rise in spite of the rise in its cost as well as the cost of treating those who are addicted to the drug.

To begin with, heroin is a highly addictive drug which is also illegal. Heroine is one of the drugs that are not very easy to stop using, thanks to its highly addictive nature and to its adverse withdrawal symptoms. Millions of those using heroine are too scared of its withdrawal effects to even attempt quitting it.  Heroin is made from the resin of poppy plants. Milky, sap-like opium is first removed from the pod of the poppy flower. This opium is refined to make morphine after further refined into different forms of heroin.

Being that the drug is mostly injected; those using this drug do not face its withdrawal side effects but also has high risks of acquiring other diseases that can be transmitted through sharing needles like HIV/AIDS.

How much do Heroin addicts spend on it heroin?

Heroine is one of the rare commodities whose increase in price do not interfere with its consumption. This drug is just as expensive as cocaine as or even slightly more than cocaine in other places but still people use it more in some places than even cocaine. Therefore, there must be some other reasons why people are turning to the use of heroine as opposed to other drugs. The factors that drive people to use of cocaine may not be new and we will explore them in this article. However, there is more than one way to look at the cost of heroine. Some people opine that the cost of heroine just like other goods and services depends on demand and supply and this may be true so it is better to stay away from using this drug even when it is being sold at a throw away price since you may not afford it later when you are now dependent on it. It is quite funny that when it comes to addictive drugs you will be able to access them for free from addicts who are ready to share them with you but when you have become dependent you shall have to find your own ways of getting your daily heroin.

Heroin

There are some hidden costs of using heroin that most people do not even think of. Most people will only be wary of the price of acquiring their daily heroin dosages for their recreational use but they give a blind eye to the real cost that arises when you need to be cured from the side effects of this drug.  A 2000 survey by the U.S. Government found that the cost of heroin addiction to our country may be anywhere from $15 billion to $20 billion dollars per year. Most of this tremendous figure is due to the price tag on treating medical conditions associated with IV heroin use – specifically, HIV/AIDS and hepatitis. The use of heroin has another hidden cost– the societal ills cost. This is the cost that you and I pay when these addicts turn to crime just in a bid to find   money to buy their much needed heroine doses daily.

The cost of getting your daily dosage of heroin to fulfill your craving cannot be compared to the cost of treating all the ills that come with using the drug. The sad truth however is, most people who are using heroin cannot afford to cater for the cost to treat the side effects that come with it. The cost of treating a heroin addict is too expensive to be compared to the mere cost of obtaining a daily dosage no matter how long you are top use the drug before you seek medical attention.

Some of the side effects of heroin

Heroine is often used mainly because of the euphoria that sets in immediately it is used but afterwards a feeling of drowsiness sets in. Just like other drugs of abuse, heroin has myriads of side effects. These may include;

  • Shortness of breath
  • Dry mouth
  • Constricted (small) pupils
  • Sudden changes in behavior or actions
  • Disorientation
  • Cycles of hyper alertness followed by suddenly nodding off
  • Droopy appearance, as if extremities are heavy

Another serious problem with heroine is because of the way it is taken. Mostly heroin is injected. Unfortunately these needles are often shared increasing the spread of such diseases as HIV/AIDS and hepatitis among other diseases. Dependence on heroin is also dangerous.

Heroin overdose is dangerous

heroinOne of the serious problems that will arise in case of heroin overdose is death. Does that sound scary? Even as scary as it sounds many people still indulge in using heroin for mere recreational purposes. However there are measures that are put in place to treat heroin overdose.  Methadone (Dolophine, Methadose) and buprenorphine among other drugs are today used for treatment of heroin overdose. These drugs block the opioid receptors in the brain hence stops the effects of the heroin. However the use of these drugs is highly regulated in different states and hence may not be very accessible to a street user of heroin.

Finally, you need more information to stay away from dependence on heroin and other drugs as these have crippled societies and that is why here at AWAREmed we are dedicated to finding the best solutions to addiction and dependence on substances. Dr. Dalal Akoury (MD) is always in the mood of helping any patient to be addiction free. Do not hesitate to call on her for help in managing any sort of chronic pain or any type of addiction as well as other diseases.

 Heroin on the Rise despite its High Cost of Treatment

 

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Are Herbicides Leading to Cancer

Herbicides and Cancer Risk

Herbicides are a class of chemicals used in agriculture. Most products containing herbicides are used in our farms and homes to control weeds and pests. These chemicals can find their way into our water and foods. When herbicides are used in plants, they end up remaining in the plant and are consumed in the food when we eat it.

Herbicides are used in all agricultural settings. It is therefore hard to do away with them if your crops are to remain healthy and yield expected results. However, there are crops that are grown without the application of herbicides.

Biotech agriculture has spread rapidly. Farmers are widely dependant on chemicals to increase yields. These chemicals have been linked to health conditions such as cancer. One of the causative factors for cancer is chemicals found in agricultural chemicals.

Most of the foods that we consume if not genetically modified is grown from chemicals such as herbicides and pesticides. These chemicals find their way into our body metabolism. This causes them to alter our body function which has been shown to greatly contribute to diseases such as cancer.

herbicides-and-cancer

Cancer is referred to as a lifestyle disease. The food you chose to eat defines your lifestyle. If your diet is mostly composed of chemical induced foods then the more likely you are at the risk of getting terminal illnesses. Refusing to regularly take exercises defines your lifestyle as well.

Exposure to herbicides occurs repeatedly and unknowingly. They are applied in different settings. Herbicides are sprayed on crops where they remain and are ingested finally in the food when we eat it. The chemicals in herbicides can also find their way into our homes through water. They are often not filtered out from our water and we end up drinking them.

Facts about Cancer

One of the factors that have been linked to cancer is chemicals. Others include, diet, lack of enough exercise, inheritance of cancer genes and infections. Cancers refer to uncontrollably growing cells in the body. This occurs when the cells are destroyed by things like chemicals. This causes cells to lose their control functions.

Cells then begin to grow uncontrollably and this leads to development of lump tissues called tumors. These tumors become toxic and end up affecting the body functioning. The cancer cells starve normal cells of energy as they consume a valuable amount of it. They grow very rapidly that they render normal cells useless.

They then start spreading to other parts of the body. They produce toxics that harm normal cells and this translates to the severe pain experienced by cancer patients.

The most common management of cancer is through surgery. Surgery is conducted on the patient to remove the cancerous tumors before they spread to other parts. If this does not work other methods such as radiation or chemo therapy are applied to kill the cancer cells and stop their growth. Others include immune therapy, stem cells transplant and many others.

How Herbicides Increase Cancer Risks

Chemicals in herbicides act as oestrogen. In normal conditions oestrogen is very important in the body. Aside from the role it plays in the reproductive cycle, it also increases essential cholesterol, maintains elasticity of blood vessels and strengthens bones for calcium absorption.

However accumulation of too much oestrogen can cause untold problems to cells by increasing their growth as well as multiplication. Increasing number of cells end up forming tumors. For this reason oestrogen is linked to breast cancer in females.

There are very many kinds of oestrogens. The natural body oestrogen is known as strong oestrogen while that found in plant foods is called weak oestrogen. Weak oestriogen counterbalances strong oestrogens and they both circulate in the body.

Herbicides causing cancer

There is also chemical oestrogen that is found in herbicides and pesticides which act like body oestrogens. All types of oestrogens work by locking onto cell receptors. High level of oestrogen in the body increases your risk of cancer.

Herbicides are continually used in agricultural setting to kill weeds and pests. The chemicals in the herbicides remain in the plant and they are ingested. Continually ingesting food grown with pesticides increases the amount of chemical oestrogen in the body. This then alters normal cell functioning leading then to grow rapidly and out of control.

In this way, chemicals found in pesticides can increase your potential for cancer. When the cells over grow they form tumors which can be cancerous. Washing vegetables and fruits well can be a remedy against consuming these chemicals found in herbicides.

Dr. Dalal Akoury has been in the medical practice for many years. She has a wide experience with cancer patients and most of them owe their health improvements to her. You too can be a part of the AwareMed community.

Can Herbicide Cause Cancer

 

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Workaholism-An Addiction Or A Quality To Be Appreciated?

Is Workaholism An Addiction Or A Quality To Be Appreciated?

workaholismNo company would be willing to employ a lazy bone, someone who will not take his work seriously, takes the least time at work and yields too little, very social but not very committed to the staff goals and objectives. Such a person has no place in the employment world. Every company would be willing to employ people who are committed to the company goals and can go an extra mile like working overtime when need be for the benefit of the company, somebody whose work helps the company to achieve great milestones and increases the output of the company. However we need to know where the boundary lies as there are people who will spend all their time in the workplace ignoring the other facets of life, they are engraved in the jobs they do so much that they become synonymous to their offices, they spend most of their lifetime working and they seem not know when to stop working and attend to their other facets of life- the workaholics.

What is Workaholism?

This refers to compulsiveness about working; a person who is subject to workaholism is referred to a workaholic. He cares more for work than any other thing to him he will work even if what he is doing is unnecessary, life without work means no sense to him. Workaholism is something that has not been addressed well and so many people who are suffering from this situation may be blinded by mere congratulations that they receive by bosses who might be aware these people’s relationship with work is abnormal. In fact the workaholics are exploited at the expense of their own social lives, they suffer broken families and some do not even marry as they are always at work and do not even attend social events where they could meet their potential spouses. Workaholics can only be good employees but are very poor in parenting and so are mostly involved in family feuds. Workaholism involves excessive time spent working, preoccupation with work to the exclusion of other life facets, loss of control over the parameters of one’s work and disenchantment with work, and negative social, emotional, and health consequences. The etiology of workaholism is not clear but may pertain to persons with compulsive personality traits, who are driven to work harder than that demanded from work contexts, and who have learned to place work as a main means of gratification compared to other lifestyle alternatives. As they spend most of their time occupied with work seeking gratification through work they may become affected health wise and so there is need for workaholics to professional help.

Is it an Addiction or a Quality to be appreciated?

Work addiction unlike other addictive life practices like sex, drug use and even gambling is little understood. There is scarcity of literature on the issue of work addiction and therefore a gap for those seeking to know more about workaholism. The subject of workaholism or addiction to work has been debated and still is being debated as to whether it is a quality to be appreciated or a serious problem that needs professional help. While many employers have viewed workaholics as a productive people workaholism has been linked to some issues both socially and as a family. In one study it was found that workaholics burden their children with roles as they are mostly away working and cannot accomplish most of their responsibilities, their children therefore begin their parental roles much younger and when they are still incapable to handle such stuff. Some of the problems that are associated with work addiction include the following.

Frustration and agitation

Just like any other person chained to other addictive behaviors a person who is addicted to work will suffer when they are forced to stop working even for just a day. They will be agitated and frustrated as work has become their only source of measuring success. It is therefore clear that workaholism is just another addiction that should be addressed just as much as drug addiction and other addictive behaviors like gambling. The fact that there is no law that workaholics break by overworking has only made matters worse for families of these people.

Low energy levels

Workaholics suffer  low energy levels as they always have work that never stops spilling over to other aspects of their lives, workaholics can stop doing other healthy practices like exercise and good nutrition just to continue working and can lead to other health issues like obesity and even increased risk to other diseases some symptoms that have been seen in workaholic include; sleep disorders, weight gain , role conflicts with fellow workers , taking sick-leave , high blood pressure, anxiety and depression and physical pain that may be caused by strain in the body muscles. These people lack control of their work and are overcommitted therefore leading to emotional exhaustion.

Workaholism

Conflict both at work and home

Workaholics are not very social people. They do not value relationships and hence spend most of their time away from their families therefore they create a gap that they ought to fill as parents- spending time with those who depend on them. This often results in conflict that may even cause a breakup between a man and his wife. Needless to mention children of workaholics grow up craving for parental love as most of the time their workaholic parent will be away from them. At work their over commitment nature will always create a gap between him and other employees as he is always in a hurry trying to accomplish a lot therefore will not have time for lunch break charts and grapevine engagements that work well in creating a bonded work family.

Finally, the topic of work addiction has attracted lots of debate but still there is little literature on this issue but from the negative aspects associated with it, it is clear that it is not really profitable to a worker. Dr. Dalal Akoury (MD) of AWAREmed Health and Wellness Resource Center is committed to availing help to addicts by availing some of the most integrative approaches to healing an addict chained to any behavior. Call on Dr. Dalal Akoury (MD) at Myrtle Beach, South Carolina for help.

Is Workaholism An Addiction Or A Quality To Be Appreciated?

 

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