Tag Archives: obesity and neurotransmitters dysfuntion

Neurotransmitters balance

Neurotransmitters balance

Neurotransmitters balance for good life is essential in all dimensions

Neurotransmitters balance for good life: The threats of the imbalance

Why is it important that every human being should have good neurotransmitters balance? And what exactly are these neurotransmitters? We spoke to Doctor Dalal Akoury MD President and founder of AWAREmed Health and Wellness Resource Center about this to get some answers. In her decades of experience in medicine, doctor Akoury is registering that neurotransmitter imbalances can actually cause problems in very many ways including those relating to moods, memory, addictions, energy, libido, and sleep. As we progress into the discussion, doctor Akoury is posing some question to you to help you re-evaluate your position.

  • Do you have any area of your life where you feel you don’t have control over?
  • Are you a shopaholic, Chocoholic, caffeine addict, or worse?
  • And finally, do you get depressed for no good reason, feel overwhelmed by life, have trouble falling asleep, or are you harboring negative thoughts that you just can’t shake?

Did I speak your mind? It is important to note that if you answer yes to any of these questions, then it’s possible that you have a neurotransmitter imbalance and this needs to be corrected if you have to be in proper control over your life. That now brings us to the next question.

Neurotransmitters balance for good life: What are the neurotransmitters?

It may surprise you to note that the brain of a normal human being is composed of billions and billions of neurons which are the cells that communicate with each other via chemical messengers known as neurotransmitters. It, therefore, means that the defining features of drug intoxication and addiction can be traced to disruptions in cell-to-cell signaling.

Drugs of abuse alter the way people think, feel, and behave by disrupting neurotransmission, the process of communication between brain cells. Over the past few decades, studies have established that drug dependence and addiction are features of an organic brain disease caused by drugs’ cumulative impacts on neurotransmission. Scientists continue to build on this essential understanding with experiments to further elucidate the physiological basis for drug abuse vulnerability as well as the full dimensions and progression of the disease. The findings provide powerful leads to new medications and behavioral treatments.

Finally, now that you know the implications of not taking why you need to balance neurotransmitters, it will be of great help to you to periodically consult with experts like Doctor Dalal Akoury for any concerns you may be having as far as balancing neurotransmitter is concerned. Upon scheduling for that appointment, doctor Akoury together with her team of experts will professionally attend to you and before you knew it, you will have your life back.

Neurotransmitters balance for good life: The threats of the imbalance



Understanding the substance Cocaine and Adderall Ritalin

Understanding the substance Cocaine and Adderall Ritalin: Why Ritalin can be addictive

mesolimbic dopamine system

Understanding the substance Cocaine and Adderall Ritalin is very crucial if we are to defeat all the elements of addiction that are associated with it.

Understanding the substance Cocaine and Adderall Ritalin begins by first appreciating their roles into the brain. These drugs can be very addictive if taken in higher doses. In fact Ritalin works by increasing the dopamine output in the brain, which helps to improve concentration. Dopamine is also the neurotransmitter very much associated with reward and pleasure in the brain, and for this reason when Ritalin is taken in higher doses than the recommended amounts it can result in euphoria. Anything that causes a psychotropic reaction (a high) can result in a psychological addiction, and Ritalin is no different. Patients with ADHD who require Ritalin therapy are given the medication in gradually increasing dosages to slowly and steadily build up base levels of dopamine in the brain, and when this process occurs over time and in a controlled manner, there is no intoxication, and there is no risk of addiction.

Understanding the substance Cocaine and Adderall Ritalin: Addictive if abused

When people take the medication for non-clinical reasons, they tend to take a higher dosage, do get high, and with prolonged abuse do find themselves addicted. Adults and children taking the medication for a legitimate medical condition, and following a doctor’s recommendations for dosage amounts and frequency, have little to worry about. Adults prescribed Ritalin sometimes do experiment with higher doses, and there have been thousands of cases where parents may also take and abuse their children’s medications. Although not as potent as a strict amphetamine, the abuse of Ritalin can be quite pleasurable, and is also associated positively with weight loss, and as such can be quite tempting.

Understanding the substance Cocaine and Adderall Ritalin: Ritalin withdrawal symptoms

Doctor Dalal Akoury says that once a person becomes addicted to Ritalin, when they try to stop taking the drug, they will experience a syndrome of withdrawal symptoms. These symptoms of withdrawal include: Tiredness, anxiety, depression, lethargy, hunger, cravings and many other symptoms.

The withdrawal and detox off of Ritalin presents very similarly to other psycho stimulants like crystal meth and cocaine, and the symptoms are predominantly internal and psychological in nature. Detox can best be accomplished in a facility away from access to the drug, and with the prescription of appropriate psychiatric medications that can take the edge off the depression and anxiety.

Understanding the substance Cocaine and Adderall Ritalin: Adderall

Adderall is commonly prescribed to patients who have difficulty controlling their actions, maintaining focus, or staying awake. It contains the active ingredients dextro-amphetamine and levo-amphetamine, both of which are psycho-stimulant amphetamine molecules. Adderall was first introduced into the public in 1996 as an instant-release (IR) drug by Shire Pharmaceuticals. In 2006, a new version, Adderall extended release (XR), was made available as well. While the instant-release drug requires 3 hours to reach its maximum plasma concentration after consumption, the extended release version takes up to 7 hours to do so. Some of the known side effects of Adderall include insomnia, loss of appetite, nausea, and hallucination. Adderall has been found to be addictive and dangerous to the health of some patients. Several withdrawal symptoms include panic attacks, seizure, fatigue

, and depression.

Understanding the substance Cocaine and Adderall Ritalin: The Chemistry and Mechanisms behind Adderall

The structure and action of Adderall resembles that of recreational drugs such as methamphetamine and MDMA (3,4-Methylenedioxymethamphetamine) (also known as ecstacy). Adderall is a phenylalkylamine, consisting of a phenyl ring and nitrogen group. The molecular resemblance of Adderall to catecholamine neurotransmitters underlies the similarities in physiological function between Adderall and these natural neurotransmitters.

The amphetamines in Adderall can bind to receptors that are normally activated by specific catecholamines produced by different glands in the body (including the hypothalamus and adrenal medulla). Amphetamine can also result in the release of more neurotransmitters that can activate sensory regions throughout the nervous system. When these psycho-stimulants activate receptors in the brain, the emotional response consists of euphoria, insomnia, increased alertness, and, sometimes, anxiety or psychosis. Peripherally, the binding of amphetamine compounds to catecholamine receptors can result in a physical response that may include the vasoconstriction of blood vessels, tachycardia, and hypertension.

In addition to stimulating the release of catecholamines, the amphetamines in Adderall also inhibit the function of monoamine transporters, which function in the re-uptake and recycling of catecholamine neurotransmitters in order to terminate the neural signal by removing the neurotransmitters from the synapse. In effect, Adderall stimulates sensory systems by maintaining the concentration of neurotransmitter in the synapse. Adderall also partakes in a “reverse-transport” or efflux process in which the amphetamines are transported from the synapse through the transporters into the presynaptic neurons and the catecholamines are simultaneously transported from the presynaptic neurons through the transporter into the synapse. This leads to an increased concentration of neurotransmitters in the synapse, allowing them to trigger receptors and activate the neuropsychological effects mentioned above. Finally, amphetamine and its analogs also enhance the synaptic neurotransmitter concentration by acting as competitive inhibitors of monoamine oxidase (MAO), an enzyme that breaks down monoamine neurotransmitters. In all these if you want to be safe, it is necessary that you keep in constant consultation with the experts from AWAREmed Health and Wellness Resource Center under the able leadership of doctor Dalal Akoury and you will not be caught an aware.

Understanding the substance Cocaine and Adderall Ritalin: Potential for Abuse

Adderall has high risk for dependence and addiction. It is hypothesized that the addictive characteristics of Adderall are due to the activation of the mesolimibic dopaminergic pathway, in which the amphetamine in the drug binds to the transporter of the neurotransmitter dopamine to prevent removal of dopamine from the synaptic cleft. By prolonging the presence of dopamine in the synapse, amphetamine produces the long-lasting side-effects of euphoria, pleasure, and concentration. In addition, the highly connected neural circuits in the central nervous system can transport dopamine from one part of the brain to another, resulting in the proliferation of the chemical signal.

Adderall abuse can also cause dangerous physiologic effects such as hypertension, seizures, and mydriasis (dilation of the pupil). Increase in blood pressure is thought to be caused by the continued release of norepinephrine. The constant stimulation of nerve receptors is the mechanism behind Adderall addiction. With continued use over time, a tolerance is developed to Adderall, as seen with other addictive drugs as well – the more frequently these drugs, including Adderall, are used, the greater the amount that is needed to supply a response. The reinforcement behavior produced by Adderall can eventually cause long-term dependence.

Research has found that under some circumstances, Adderall can induce psychosis in adolescents comparable to schizophrenia. Though the precise mechanism is not clear, it is possible that this effect is due to an increased amphetamine-induced dopamine release. The symptoms cleared in patients who withdrew from using Adderall. The chemical similarity between natural neurotransmitters in the body and Adderall increases both the likelihood and degree of abuse. Thus, until the risks of psycho-stimulants are understood in more detail, it is advisable to remain cautious about prescribing Adderall to those with ADHD.

Understanding the substance Cocaine and Adderall Ritalin: Why Ritalin can be addictive



Neurotransmitters dysfunction and obesity

Neurotransmitters dysfunction

Neurotransmitters are the naturally occurring chemicals inside your body that transmit messages between nerve cells. In the brain alone there are 183 different neurotransmitters. Two major neurotransmitters are…..


Neurotransmitters are naturally occurring chemicals that “transmit” electrical messages between nerve cells, called “neurons” hence the name neurotransmitters. They are produced in the body by amino acids with the help of vitamins and minerals. We get these amino acids, vitamins and minerals from the food we eat. However, if we are not getting enough of these or in an imbalanced ratio a deficiency occurs and over time can lead to the development of diseases and illnesses associated with low levels of neurotransmitters.

What diseases are associated with neurotransmitter dysfunction?

According to Neuro-Research a list of diseases or illnesses are caused by or associated with neurotransmitter dysfunction. Neurotransmitter dysfunction leads to obesity and the diseases resulting from obesity, as well as other diseases not associated with obesity. Causes of neurotransmitter dysfunction There are four known primary causes of neurotransmitter dysfunction. 1: Nutritional Deficiency 2: Prescription drugs 3: Damage to the neurons of the brain 4: Excess excretion of neurotransmitters by the kidneys

 Neurotransmitter dysfunction -Why is lab testing only used after starting amino acid therapy?

This is a common question. We are used to a medical community that runs tests first and then treats based on the test. However with neurotransmitters, hyper excretion is a common problem. Hyper excretion results when the kidneys are excreting excessive amounts of neurotransmitters so that the urinary values don’t match up with the systemic values. Once treatment starts with amino acids this problem doesn’t seem to occur. Therefore testing is NOT performed prior to supplementation with amino acids.

Neurotransmitter dysfunction -How many supplements are involved in treatment and what is each doing?

There are two different programs available for treatment. The first specifically treats neurotransmitter dysfunction resulting in the “conditions related to obesity and neurotransmitter deficiency” listed right. The second program treats neurotransmitter dysfunction as well as weight loss by incorporating an appetite suppressant in the formula. This will assist in controlling your appetite, however, calorie restriction is still necessary to accomplish long-term weight loss. This second program can also be used to treat symptoms associated with Parkinsonism. If only one neurotransmitter system is not functioning properly, why do I have to take supplements that affect both systems? The reason is simple, according to Neuro-Research’s extensive research, they have found that 5% of patients have only serotonin dysfunction, 5% of patients have only catecholamine dysfunction and 90% of patients are a mixture of both. Both systems must be functioning properly for the entire system to be healthy and free of neurotransmitter disease. After you have started the program we will monitor your symptoms and lab test results and adjust the supplements accordingly. So in the end you may take more of one supplement than another to achieve an appropriate “balance”. More about the Neurotransmitter Support Supplements available! Proteins, minerals, vitamins, carbohydrates, and fats are the essential nutrients that make up your body. Proteins are the essential components of muscle tissue, organs, blood, enzymes, antibodies, and neurotransmitters in the brain. Your brain needs the proper nutrients every day in order to manufacture proper levels of the neurotransmitters that regulate your mood. Neurotransmitter Effects:

  1. Control the appetite center of the brain.
  2. Stimulates Corticotrophin Releasing Factor, Adrenocorticotropic Hormone, & Cortisol.
  3. Regulate male and female sex hormone.
  4. Regulates sleep.
  5. Modulate mood and thought processes.
  6. Controls ability to focus, concentrate, and remember things.
  7. The Mind Body Connection.
  8. The chemistry of our bodies can alter, and be altered by our every thought and feeling. Our bodies and our minds are truly interconnected; the health of one depends on the health of the other.

There are many biochemical neurotransmitter imbalances that result in mental health symptoms such as:

  1. Adrenal dysfunction
  2. Blood sugar imbalance
  3. Food and Chemical allergy
  4. Heavy Metal Toxicity
  5. Hormone imbalance
  6. Nutritional Deficiency
  7. Serotonin/Dopamine/Noradrenalin imbalance
  8. Stimulant and drug intoxication
  9. Under or overactive thyroid

  Neurotransmitter Imbalances Disrupted communication between the brain and the body can have serious effects to one’s health both physically and mentally. Depression, anxiety and other mood disorders are thought to be directly related to imbalances with neurotransmitters. The four major neurotransmitters that regulate mood are Serotonin, Dopamine, GABA and Norepinephrine.

Neurotransmitter dysfunction -The Inhibitory System

Neurotransmitters dysfunction

Neurotransmitter system dysfunction may contribute to the borderline personality disorder traits of impulsive aggression and affective instability

This is the brains braking system, it prevents the signal from continuing. The inhibitory system slows things down. Serotonin and GABA are examples of inhibitory neurotransmitters. GABA (Gamma amino butyric acid) GABA is the major inhibitory neurotransmitter in the central nervous system. It helps the neurons recover after transmission, reduces anxiety and stress. It regulates norepinephrine, adrenaline, dopamine, and serotonin; it is a significant mood modulator. Serotonin imbalance This is one of the most common contributors to mood problems. Some feel it is a virtual epidemic in the United States. Serotonin is key to our feelings of happiness and very important for our emotions because it helps defend against both anxiety and depression. You may have a shortage of serotonin if you have a sad depressed mood, anxiety, panic attacks, low energy, migraines, sleeping problems, obsession or compulsions, feel tense and irritable, crave sweets, and have a reduced interest in sex. Additionally, your hormones and Estrogen levels can affect serotonin levels and this may explain why some women have pre-menstrual and menopausal mood problems. Moreover, daily stress can greatly reduce your serotonin supplies. The Excitatory Neurotransmitter System This can be related to your car’s accelerator. It allows the signal to go. When the excitatory neurotransmitter system is in drive your system gets all raved up for action. Without a functioning inhibitory system to put on the brakes, things (like your mood) can get out of control. Among other things, the following should be in place to restore neurotransmitters in attempt to achieve weight loss.   Epinephrine It’s also known as adrenaline is a neurotransmitter and hormone essential to metabolism. It regulates attention, mental focus, arousal, and cognition. It also inhibits insulin excretion and raises the amounts of fatty acids in the blood. Epinephrine is made from norepinephrine and is released from the adrenal glands. Low levels have been can result in fatigue, lack of focus, and difficulty losing weight. High levels have been linked to sleep problems, anxiety and ADHD.   Dopamine It’s responsible for motivation, interest, and drive. It is associated with positive stress states such as being in love, exercising, listening to music, and sex. When we don’t have enough of it we don’t feel alive, we have difficulty initiating or completing tasks, poor concentration, no energy, and lack of motivation. Dopamine also is involved in muscle control and function. Low Dopamine levels can drive us to use drugs (self-medicate), alcohol, smoke cigarettes, gamble, and/or overeat. High dopamine has been observed in patients with poor GI function, autism, mood swings, psychosis, and children with attention disorders. Glutamate It’s the major excitatory neurotransmitter in the brain. It is required for learning and memory. Low levels can lead to tiredness and poor brain activity. Increased levels of glutamate can cause death to the neurons (nerve cells) in the brain. Dysfunction in glutamate levels are involved in many neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s, Huntington’s, and Tourette’s. High levels also contribute to Depression, OCD, and Autism. Neurotransmitter Levels Neurotransmitter levels can now be determined by a simple and convenient urine test collected at home. Knowing your neurotransmitter levels can help you correct a problem today or prevent problems from occurring in the future.

Neurotransmitters dysfunction and obesity-Exposition


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